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Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy

Michael P. Vincent, Trevor Stack, Amir Vahabikashi, Guorong Li, Kristin M. Perkumas, Ruiyi Ren, Haiyan Gong, W. Daniel Stamer, Mark Johnson, Evan A. Scott
doi: https://doi.org/10.1101/2021.05.19.444878
Michael P. Vincent
1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
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Trevor Stack
1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
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Amir Vahabikashi
2Department of Cell and Developmental Biology, Northwestern University, Northwestern University, Chicago, IL 60611, USA
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Guorong Li
3Department of Ophthalmology, Duke University, Durham, NC 27710, USA
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Kristin M. Perkumas
3Department of Ophthalmology, Duke University, Durham, NC 27710, USA
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Ruiyi Ren
4Department of Ophthalmology, Boston University School of Medicine, Boston, MA 02118, USA
5Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
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Haiyan Gong
4Department of Ophthalmology, Boston University School of Medicine, Boston, MA 02118, USA
5Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
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W. Daniel Stamer
3Department of Ophthalmology, Duke University, Durham, NC 27710, USA
6Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
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Mark Johnson
1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
7Department of Ophthalmology, Northwestern University, Chicago, IL 60611, USA
8Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA
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Evan A. Scott
1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
9Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA
10Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
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  • For correspondence: evan.scott@northwestern.edu
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Article Information

doi 
https://doi.org/10.1101/2021.05.19.444878
History 
  • May 20, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Michael P. Vincent1,
  2. Trevor Stack1,
  3. Amir Vahabikashi2,
  4. Guorong Li3,
  5. Kristin M. Perkumas3,
  6. Ruiyi Ren4,5,
  7. Haiyan Gong4,5,
  8. W. Daniel Stamer3,6,
  9. Mark Johnson1,7,8 and
  10. Evan A. Scott1,9,10,*
  1. 1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
  2. 2Department of Cell and Developmental Biology, Northwestern University, Northwestern University, Chicago, IL 60611, USA
  3. 3Department of Ophthalmology, Duke University, Durham, NC 27710, USA
  4. 4Department of Ophthalmology, Boston University School of Medicine, Boston, MA 02118, USA
  5. 5Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
  6. 6Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
  7. 7Department of Ophthalmology, Northwestern University, Chicago, IL 60611, USA
  8. 8Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA
  9. 9Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA
  10. 10Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
  1. ↵*Corresponding Author E-mail: evan.scott{at}northwestern.edu.
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Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy
Michael P. Vincent, Trevor Stack, Amir Vahabikashi, Guorong Li, Kristin M. Perkumas, Ruiyi Ren, Haiyan Gong, W. Daniel Stamer, Mark Johnson, Evan A. Scott
bioRxiv 2021.05.19.444878; doi: https://doi.org/10.1101/2021.05.19.444878
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Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy
Michael P. Vincent, Trevor Stack, Amir Vahabikashi, Guorong Li, Kristin M. Perkumas, Ruiyi Ren, Haiyan Gong, W. Daniel Stamer, Mark Johnson, Evan A. Scott
bioRxiv 2021.05.19.444878; doi: https://doi.org/10.1101/2021.05.19.444878

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