Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

A Spatiotemporal Map of Reading Aloud

View ORCID ProfileOscar Woolnough, View ORCID ProfileCristian Donos, View ORCID ProfileAidan Curtis, View ORCID ProfilePatrick S. Rollo, Zachary J. Roccaforte, View ORCID ProfileStanislas Dehaene, View ORCID ProfileSimon Fischer-Baum, View ORCID ProfileNitin Tandon
doi: https://doi.org/10.1101/2021.05.23.445307
Oscar Woolnough
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
2Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Oscar Woolnough
Cristian Donos
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
3Faculty of Physics, University of Bucharest, 050663, Bucharest, Romania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Cristian Donos
Aidan Curtis
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Aidan Curtis
Patrick S. Rollo
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
2Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Patrick S. Rollo
Zachary J. Roccaforte
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
2Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stanislas Dehaene
4Cognitive Neuroimaging Unit CEA, INSERM, NeuroSpin Center, Université Paris-Sud and Université Paris-Saclay, 91191, Gif-sur-Yvette, France
5Collège de France, 11 Place Marcelin Berthelot, 75005, Paris, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Stanislas Dehaene
Simon Fischer-Baum
6Department of Psychological Sciences, Rice University, Houston, TX, 77005, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Simon Fischer-Baum
Nitin Tandon
1Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, 77030, United States of America
2Texas Institute for Restorative Neurotechnologies, University of Texas Health Science Center at Houston, Houston, TX, 77030, United States of America
7Memorial Hermann Hospital, Texas Medical Center, Houston, TX, 77030, United States of America
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Nitin Tandon
  • For correspondence: nitin.tandon@uth.tmc.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Reading words aloud is a foundational aspect of the acquisition of literacy. The rapid rate at which multiple distributed neural substrates are engaged in this process can only be probed via techniques with high spatiotemporal resolution. We used direct intracranial recordings in a large cohort to create a holistic yet fine-grained map of word processing, enabling us to derive the spatiotemporal neural codes of multiple word attributes critical to reading: lexicality, word frequency and orthographic neighborhood. We found that lexicality is encoded by early activity in mid-fusiform (mFus) cortex and precentral sulcus. Word frequency is also first represented in mFus followed by later engagement of the inferior frontal gyrus (IFG) and inferior parietal sulcus (IPS), and orthographic neighborhood is encoded solely in the IPS. A lexicality decoder revealed high weightings for electrodes in the mFus, IPS, anterior IFG and the pre-central sulcus. These results elaborate the neural codes underpinning extant dual-route models of reading, with parallel processing via the lexical route, progressing from mFus to IFG, and the sub-lexical route, progressing from IPS to anterior IFG.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted May 23, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
A Spatiotemporal Map of Reading Aloud
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
A Spatiotemporal Map of Reading Aloud
Oscar Woolnough, Cristian Donos, Aidan Curtis, Patrick S. Rollo, Zachary J. Roccaforte, Stanislas Dehaene, Simon Fischer-Baum, Nitin Tandon
bioRxiv 2021.05.23.445307; doi: https://doi.org/10.1101/2021.05.23.445307
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
A Spatiotemporal Map of Reading Aloud
Oscar Woolnough, Cristian Donos, Aidan Curtis, Patrick S. Rollo, Zachary J. Roccaforte, Stanislas Dehaene, Simon Fischer-Baum, Nitin Tandon
bioRxiv 2021.05.23.445307; doi: https://doi.org/10.1101/2021.05.23.445307

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (4239)
  • Biochemistry (9161)
  • Bioengineering (6798)
  • Bioinformatics (24055)
  • Biophysics (12152)
  • Cancer Biology (9564)
  • Cell Biology (13822)
  • Clinical Trials (138)
  • Developmental Biology (7654)
  • Ecology (11734)
  • Epidemiology (2066)
  • Evolutionary Biology (15538)
  • Genetics (10667)
  • Genomics (14355)
  • Immunology (9507)
  • Microbiology (22889)
  • Molecular Biology (9122)
  • Neuroscience (49099)
  • Paleontology (357)
  • Pathology (1487)
  • Pharmacology and Toxicology (2580)
  • Physiology (3851)
  • Plant Biology (8349)
  • Scientific Communication and Education (1473)
  • Synthetic Biology (2301)
  • Systems Biology (6204)
  • Zoology (1302)