Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Precise visuomotor transformations underlying collective behavior in larval zebrafish

View ORCID ProfileRoy Harpaz, Minh Nguyet Nguyen, View ORCID ProfileArmin Bahl, Florian Engert
doi: https://doi.org/10.1101/2021.05.24.445521
Roy Harpaz
1Department of Molecular and Cellular Biology, Harvard University, Cambridge 02138, USA
2Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Roy Harpaz
  • For correspondence: harpazone@gmail.com
Minh Nguyet Nguyen
3Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Armin Bahl
4Centre for the Advanced Study of Collective Behaviour, University of Konstanz, Konstanz 78464, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Armin Bahl
Florian Engert
1Department of Molecular and Cellular Biology, Harvard University, Cambridge 02138, USA
2Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Complex schooling behaviors result from local interactions among individuals. Yet, how sensory signals from neighbors are analyzed in the visuomotor stream of animals is poorly understood. Here, we studied aggregation behavior in larval zebrafish and found that over development larvae transition from overdispersed groups to tight shoals. Using a virtual reality assay, we characterized the algorithms fish use to transform visual inputs from neighbors into movement decisions. We found that young larvae turn away from retinal “clutter” by integrating and averaging retina-wide visual inputs within each eye, and by using a winner-take-all strategy for binocular integration. As fish mature, their responses expand to include attraction to low retinal clutter, that is based on similar algorithms of visual integration. Using model simulations, we show that the observed algorithms accurately predict group structure over development. These findings allow us to make testable predictions regarding the neuronal circuits underlying collective behavior in zebrafish.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted May 25, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Precise visuomotor transformations underlying collective behavior in larval zebrafish
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Precise visuomotor transformations underlying collective behavior in larval zebrafish
Roy Harpaz, Minh Nguyet Nguyen, Armin Bahl, Florian Engert
bioRxiv 2021.05.24.445521; doi: https://doi.org/10.1101/2021.05.24.445521
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Precise visuomotor transformations underlying collective behavior in larval zebrafish
Roy Harpaz, Minh Nguyet Nguyen, Armin Bahl, Florian Engert
bioRxiv 2021.05.24.445521; doi: https://doi.org/10.1101/2021.05.24.445521

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (3686)
  • Biochemistry (7774)
  • Bioengineering (5668)
  • Bioinformatics (21245)
  • Biophysics (10563)
  • Cancer Biology (8162)
  • Cell Biology (11915)
  • Clinical Trials (138)
  • Developmental Biology (6738)
  • Ecology (10388)
  • Epidemiology (2065)
  • Evolutionary Biology (13843)
  • Genetics (9694)
  • Genomics (13056)
  • Immunology (8123)
  • Microbiology (19956)
  • Molecular Biology (7833)
  • Neuroscience (42973)
  • Paleontology (318)
  • Pathology (1276)
  • Pharmacology and Toxicology (2256)
  • Physiology (3350)
  • Plant Biology (7208)
  • Scientific Communication and Education (1309)
  • Synthetic Biology (1999)
  • Systems Biology (5528)
  • Zoology (1126)