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Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
View ORCID ProfileNeil A. Robertson, View ORCID ProfileEric Latorre-Crespo, View ORCID ProfileMaria Terradas-Terradas, Alison C. Purcell, View ORCID ProfileBenjamin J Livesey, View ORCID ProfileJoseph A. Marsh, View ORCID ProfileLee Murphy, View ORCID ProfileAngie Fawkes, Louise MacGillivray, View ORCID ProfileMhairi Copland, View ORCID ProfileRiccardo E. Marioni, View ORCID ProfileSarah E. Harris, View ORCID ProfileSimon R. Cox, View ORCID ProfileIan J. Deary, View ORCID ProfileLinus J. Schumacher, View ORCID ProfileKristina Kirschner, View ORCID ProfileTamir Chandra
doi: https://doi.org/10.1101/2021.05.27.446006
Neil A. Robertson
1MRC Human Genetics Unit, University of Edinburgh, Edinburgh, EH4 2XU, UK
Eric Latorre-Crespo
1MRC Human Genetics Unit, University of Edinburgh, Edinburgh, EH4 2XU, UK
Maria Terradas-Terradas
2Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK
3Cancer Research UK Beatson Institute, Glasgow, UK
Alison C. Purcell
2Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK
3Cancer Research UK Beatson Institute, Glasgow, UK
Benjamin J Livesey
1MRC Human Genetics Unit, University of Edinburgh, Edinburgh, EH4 2XU, UK
Joseph A. Marsh
1MRC Human Genetics Unit, University of Edinburgh, Edinburgh, EH4 2XU, UK
Lee Murphy
4Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, EH4 2XU, UK
Angie Fawkes
4Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, EH4 2XU, UK
Louise MacGillivray
4Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, EH4 2XU, UK
Mhairi Copland
2Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK
Riccardo E. Marioni
5Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK
Sarah E. Harris
6Lothian Birth Cohorts, Department of Psychology, The University of Edinburgh, Edinburgh, UK
7Department of Psychology, The University of Edinburgh, Edinburgh, UK
Simon R. Cox
6Lothian Birth Cohorts, Department of Psychology, The University of Edinburgh, Edinburgh, UK
7Department of Psychology, The University of Edinburgh, Edinburgh, UK
Ian J. Deary
6Lothian Birth Cohorts, Department of Psychology, The University of Edinburgh, Edinburgh, UK
7Department of Psychology, The University of Edinburgh, Edinburgh, UK
Linus J. Schumacher
8Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK
Kristina Kirschner
2Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK
3Cancer Research UK Beatson Institute, Glasgow, UK
Tamir Chandra
1MRC Human Genetics Unit, University of Edinburgh, Edinburgh, EH4 2XU, UK
Article usage
Posted May 28, 2021.
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
Neil A. Robertson, Eric Latorre-Crespo, Maria Terradas-Terradas, Alison C. Purcell, Benjamin J Livesey, Joseph A. Marsh, Lee Murphy, Angie Fawkes, Louise MacGillivray, Mhairi Copland, Riccardo E. Marioni, Sarah E. Harris, Simon R. Cox, Ian J. Deary, Linus J. Schumacher, Kristina Kirschner, Tamir Chandra
bioRxiv 2021.05.27.446006; doi: https://doi.org/10.1101/2021.05.27.446006
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
Neil A. Robertson, Eric Latorre-Crespo, Maria Terradas-Terradas, Alison C. Purcell, Benjamin J Livesey, Joseph A. Marsh, Lee Murphy, Angie Fawkes, Louise MacGillivray, Mhairi Copland, Riccardo E. Marioni, Sarah E. Harris, Simon R. Cox, Ian J. Deary, Linus J. Schumacher, Kristina Kirschner, Tamir Chandra
bioRxiv 2021.05.27.446006; doi: https://doi.org/10.1101/2021.05.27.446006
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