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History
- August 18, 2021.
Article Versions
- Version 1 (May 28, 2021 - 23:13).
- Version 2 (August 3, 2021 - 20:49).
- You are viewing Version 3, the most recent version of this article.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Author Information
- Songjie Chen1,2,
- Guangwen Wang1,2,
- Xiaotao Shen1,2,
- Daniel Hornburg1,
- Shannon Rego1,
- Rene Hoffman1,
- Stephanie Nevins1,
- Xun Cheng1 and
- Michael Snyder1,3
- ↵3Corresponding author: Michael Synder, email: mpsnyder{at}stanford.edu
↵2 These authors contributed equally: Songjie Chen, Guangwen Wang, and Xiaotao Shen
Author Contributions: S.C. and G.W. designed and managed the study; S.C. performed metabolomics and proteomics profiling of plasma and cell lysate samples, analysis and interpretation of data, drafting of the manuscript; G.W., R.H., S.N., X.C. generated the disease modelling iPSCs and NPCs; X.S. performed the annotation of metabolites and visualization of results. D.H. performed lipidomics profiling of plasma samples. S.R. wrote the IRB protocol and obtained approval; ensured compliance with privacy regulations; coordinated sample collection and obtained informed consent. G.W. and M.S. reviewed and edited the manuscript; M.S. supervised the project.