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Decentralizing cell-free RNA sensing with the use of low-cost cell extracts

Anibal Arce, Fernando Guzman Chavez, Chiara Gandini, Juan Puig, Tamara Matute, Jim Haseloff, Neil Dalchau, Jenny Molloy, Keith Pardee, Fernán Federici
doi: https://doi.org/10.1101/2021.05.29.446205
Anibal Arce
1ANID – Millennium Science Initiative Program – Millennium Institute for Integrative Biology (iBio), Santiago, Chile
2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile
3Departamento de Genética Molecular y Microbiología, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile
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Fernando Guzman Chavez
7Department of Plant Sciences, University of Cambridge, Downing Site, Cambridge, CB2 3EA, United Kingdom
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Chiara Gandini
6Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge, CB3 0AS, United Kingdom
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Juan Puig
1ANID – Millennium Science Initiative Program – Millennium Institute for Integrative Biology (iBio), Santiago, Chile
2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile
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Tamara Matute
1ANID – Millennium Science Initiative Program – Millennium Institute for Integrative Biology (iBio), Santiago, Chile
2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile
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Jim Haseloff
7Department of Plant Sciences, University of Cambridge, Downing Site, Cambridge, CB2 3EA, United Kingdom
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Neil Dalchau
8Microsoft Research, 21 Station Road, Cambridge, CB1 2FB, United Kingdom
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Jenny Molloy
6Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge, CB3 0AS, United Kingdom
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Keith Pardee
4Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
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Fernán Federici
1ANID – Millennium Science Initiative Program – Millennium Institute for Integrative Biology (iBio), Santiago, Chile
2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile
3Departamento de Genética Molecular y Microbiología, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile
5FONDAP Center for Genome Regulation. Santiago, Chile
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  • For correspondence: ffederici@bio.puc.cl
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Article Information

doi 
https://doi.org/10.1101/2021.05.29.446205
History 
  • May 30, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Anibal Arce1,2,3,
  2. Fernando Guzman Chavez7,
  3. Chiara Gandini6,
  4. Juan Puig1,2,
  5. Tamara Matute1,2,
  6. Jim Haseloff7,
  7. Neil Dalchau8,
  8. Jenny Molloy6,
  9. Keith Pardee4 and
  10. Fernán Federici1,2,3,5,*
  1. 1ANID – Millennium Science Initiative Program – Millennium Institute for Integrative Biology (iBio), Santiago, Chile
  2. 2Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile
  3. 3Departamento de Genética Molecular y Microbiología, Pontificia Universidad Católica de Chile, Santiago, 8331150, Chile
  4. 4Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
  5. 5FONDAP Center for Genome Regulation. Santiago, Chile
  6. 6Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge, CB3 0AS, United Kingdom
  7. 7Department of Plant Sciences, University of Cambridge, Downing Site, Cambridge, CB2 3EA, United Kingdom
  8. 8Microsoft Research, 21 Station Road, Cambridge, CB1 2FB, United Kingdom
  1. ↵*Correspondence: Fernán Federici
    , ffederici{at}bio.puc.cl
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Decentralizing cell-free RNA sensing with the use of low-cost cell extracts
Anibal Arce, Fernando Guzman Chavez, Chiara Gandini, Juan Puig, Tamara Matute, Jim Haseloff, Neil Dalchau, Jenny Molloy, Keith Pardee, Fernán Federici
bioRxiv 2021.05.29.446205; doi: https://doi.org/10.1101/2021.05.29.446205
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Decentralizing cell-free RNA sensing with the use of low-cost cell extracts
Anibal Arce, Fernando Guzman Chavez, Chiara Gandini, Juan Puig, Tamara Matute, Jim Haseloff, Neil Dalchau, Jenny Molloy, Keith Pardee, Fernán Federici
bioRxiv 2021.05.29.446205; doi: https://doi.org/10.1101/2021.05.29.446205

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