New Results
A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
View ORCID ProfileBenjamin J. Reisman, View ORCID ProfileHui Guo, Haley E. Ramsey, View ORCID ProfileMadison T. Wright, View ORCID ProfileBradley I. Reinfeld, View ORCID ProfileP. Brent Ferrell, View ORCID ProfileGary A. Sulikowski, View ORCID ProfileW. Kimryn Rathmell, View ORCID ProfileMichael R. Savona, View ORCID ProfileLars Plate, View ORCID ProfileJohn L. Rubinstein, View ORCID ProfileBrian O. Bachmann
doi: https://doi.org/10.1101/2021.05.31.445492
Benjamin J. Reisman
1Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA
2Medical Scientist Training Program, Vanderbilt University, Nashville, Tennessee, USA
Hui Guo
3Molecular Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada
4Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
Haley E. Ramsey
5Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Madison T. Wright
1Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA
Bradley I. Reinfeld
2Medical Scientist Training Program, Vanderbilt University, Nashville, Tennessee, USA
4Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
6Cancer Biology Program, Vanderbilt University, Nashville, Tennessee, USA
P. Brent Ferrell
5Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
6Cancer Biology Program, Vanderbilt University, Nashville, Tennessee, USA
Gary A. Sulikowski
1Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA
7Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, USA
W. Kimryn Rathmell
5Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
6Cancer Biology Program, Vanderbilt University, Nashville, Tennessee, USA
Michael R. Savona
5Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
6Cancer Biology Program, Vanderbilt University, Nashville, Tennessee, USA
Lars Plate
1Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA
7Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, USA
8Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
John L. Rubinstein
3Molecular Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada
4Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
9Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
Brian O. Bachmann
1Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA
7Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, USA
Article usage
Posted May 31, 2021.
A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Benjamin J. Reisman, Hui Guo, Haley E. Ramsey, Madison T. Wright, Bradley I. Reinfeld, P. Brent Ferrell, Gary A. Sulikowski, W. Kimryn Rathmell, Michael R. Savona, Lars Plate, John L. Rubinstein, Brian O. Bachmann
bioRxiv 2021.05.31.445492; doi: https://doi.org/10.1101/2021.05.31.445492
A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Benjamin J. Reisman, Hui Guo, Haley E. Ramsey, Madison T. Wright, Bradley I. Reinfeld, P. Brent Ferrell, Gary A. Sulikowski, W. Kimryn Rathmell, Michael R. Savona, Lars Plate, John L. Rubinstein, Brian O. Bachmann
bioRxiv 2021.05.31.445492; doi: https://doi.org/10.1101/2021.05.31.445492
Subject Area
Subject Areas
- Biochemistry (11745)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14972)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28085)
- Molecular Biology (11592)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7340)
- Zoology (1651)