Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Characterizing the middle-age neurophysiology using EEG/MEG

Justyna Gula, View ORCID ProfileVictoria Moiseeva, View ORCID ProfileMaria Herrojo Ruiz, View ORCID ProfileMarinella Cappelletti
doi: https://doi.org/10.1101/2021.06.04.447084
Justyna Gula
1Department of Psychology, Goldsmiths, University of London, Lewisham Way, London SE14 6NW, UK; ; ;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: justyna.j.gula@gmail.com justyna.j.gula@gmail.com m.cappelletti@gold.ac.uk M.Herrojo-Ruiz@gold.ac.uk
Victoria Moiseeva
2Institute for Cognitive Neuroscience, HSE University, 18 Myasnitskaya St, Moscow 109028, Russian Federation;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Victoria Moiseeva
  • For correspondence: vmoiseeva@hse.ru
Maria Herrojo Ruiz
1Department of Psychology, Goldsmiths, University of London, Lewisham Way, London SE14 6NW, UK; ; ;
2Institute for Cognitive Neuroscience, HSE University, 18 Myasnitskaya St, Moscow 109028, Russian Federation;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Maria Herrojo Ruiz
  • For correspondence: justyna.j.gula@gmail.com m.cappelletti@gold.ac.uk M.Herrojo-Ruiz@gold.ac.uk vmoiseeva@hse.ru
Marinella Cappelletti
1Department of Psychology, Goldsmiths, University of London, Lewisham Way, London SE14 6NW, UK; ; ;
3Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marinella Cappelletti
  • For correspondence: justyna.j.gula@gmail.com m.cappelletti@gold.ac.uk M.Herrojo-Ruiz@gold.ac.uk
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Data/Code
  • Preview PDF
Loading

ABSTRACT

Middle adulthood – the period of life between 40 and 60 years of age – is accompanied by important physical and emotional changes, as well as cognitive and neuronal ones. Nevertheless, middle age is often overlooked in neuroscience under the assumption that this is a time of relative stability, although cognitive decline, as well as changes in brain structure and function are well-established by the age of 60.

Here we characterized the middle-aged brain in the context of healthy younger and older adults by assessing resting-state electrophysiological and neuromagnetic activity in two different samples (N = 179, 631). Alpha and beta oscillations – two key ageing signatures – were analyzed in terms of spectral power and burst events. While posterior alpha power and burst rate features changed linearly with age, similarly to behavioral measures, sensorimotor beta power and burst rate properties varied non-linearly, with inflection points during middle age. The findings suggest that ageing is characterized by distinct spatial and temporal brain dynamics, some critically arising in middle age.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • https://www.cam-can.org/index.php?content=dataset

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted June 06, 2021.
Download PDF

Supplementary Material

Data/Code
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Characterizing the middle-age neurophysiology using EEG/MEG
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Characterizing the middle-age neurophysiology using EEG/MEG
Justyna Gula, Victoria Moiseeva, Maria Herrojo Ruiz, Marinella Cappelletti
bioRxiv 2021.06.04.447084; doi: https://doi.org/10.1101/2021.06.04.447084
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Characterizing the middle-age neurophysiology using EEG/MEG
Justyna Gula, Victoria Moiseeva, Maria Herrojo Ruiz, Marinella Cappelletti
bioRxiv 2021.06.04.447084; doi: https://doi.org/10.1101/2021.06.04.447084

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (4844)
  • Biochemistry (10777)
  • Bioengineering (8034)
  • Bioinformatics (27256)
  • Biophysics (13964)
  • Cancer Biology (11110)
  • Cell Biology (16026)
  • Clinical Trials (138)
  • Developmental Biology (8772)
  • Ecology (13268)
  • Epidemiology (2067)
  • Evolutionary Biology (17342)
  • Genetics (11678)
  • Genomics (15904)
  • Immunology (11013)
  • Microbiology (26044)
  • Molecular Biology (10626)
  • Neuroscience (56463)
  • Paleontology (417)
  • Pathology (1729)
  • Pharmacology and Toxicology (2999)
  • Physiology (4539)
  • Plant Biology (9614)
  • Scientific Communication and Education (1613)
  • Synthetic Biology (2683)
  • Systems Biology (6968)
  • Zoology (1508)