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Brain charts for the human lifespan
View ORCID ProfileR.A.I. Bethlehem, View ORCID ProfileJ. Seidlitz, View ORCID ProfileS.R. White, J.W. Vogel, View ORCID ProfileK.M. Anderson, View ORCID ProfileC. Adamson, View ORCID ProfileS. Adler, View ORCID ProfileG.S. Alexopoulos, View ORCID ProfileE. Anagnostou, A. Areces-Gonzalez, View ORCID ProfileD.E. Astle, View ORCID ProfileB. Auyeung, View ORCID ProfileM. Ayub, View ORCID ProfileG. Ball, View ORCID ProfileS. Baron-Cohen, R. Beare, View ORCID ProfileS.A. Bedford, View ORCID ProfileV. Benegal, View ORCID ProfileF. Beyer, J. Bin Bae, J. Blangero, View ORCID ProfileM. Blesa Cábez, View ORCID ProfileJ.P. Boardman, View ORCID ProfileM. Borzage, View ORCID ProfileJ.F. Bosch-Bayard, View ORCID ProfileN. Bourke, View ORCID ProfileV.D. Calhoun, View ORCID ProfileM.M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y.S. Chong, View ORCID ProfileJ.H. Cole, A. Corvin, E. Courchesne, View ORCID ProfileF. Crivello, View ORCID ProfileV.L. Cropley, View ORCID ProfileJ. Crosbie, N. Crossley, M. Delarue, View ORCID ProfileS. Desrivieres, G. Devenyi, View ORCID ProfileM.A. Di Biase, View ORCID ProfileR. Dolan, View ORCID ProfileK.A. Donald, G. Donohoe, View ORCID ProfileK. Dunlop, View ORCID ProfileA.D. Edwards, J.T. Elison, C.T. Ellis, View ORCID ProfileJ.A. Elman, L. Eyler, D.A. Fair, P.C. Fletcher, View ORCID ProfileP. Fonagy, View ORCID ProfileC.E. Franz, View ORCID ProfileL. Galan-Garcia, View ORCID ProfileA. Gholipour, View ORCID ProfileJ. Giedd, J.H. Gilmore, View ORCID ProfileD.C. Glahn, View ORCID ProfileI. Goodyer, View ORCID ProfileP.E. Grant, View ORCID ProfileN.A. Groenewold, View ORCID ProfileF.M. Gunning, R.E. Gur, R.C. Gur, C.F. Hammill, O. Hansson, T. Hedden, View ORCID ProfileA. Heinz, View ORCID ProfileR. Henson, View ORCID ProfileK. Heuer, J. Hoare, B. Holla, View ORCID ProfileA.J. Holmes, R. Holt, View ORCID ProfileH. Huang, View ORCID ProfileK. Im, View ORCID ProfileJ. Ipser, View ORCID ProfileC.R. Jack Jr, View ORCID ProfileA.P. Jackowski, View ORCID ProfileT. Jia, View ORCID ProfileK.A. Johnson, View ORCID ProfileP.B. Jones, View ORCID ProfileD.T. Jones, R. Kahn, View ORCID ProfileH. Karlsson, View ORCID ProfileL. Karlsson, View ORCID ProfileR. Kawashima, View ORCID ProfileE.A. Kelley, View ORCID ProfileS. Kern, K. Kim, View ORCID ProfileM.G. Kitzbichler, View ORCID ProfileW.S. Kremen, F. Lalonde, View ORCID ProfileB. Landeau, S. Lee, J. Lerch, J.D. Lewis, View ORCID ProfileJ. Li, View ORCID ProfileW. Liao, View ORCID ProfileD.P. Linares, View ORCID ProfileC. Liston, View ORCID ProfileM.V. Lombardo, View ORCID ProfileJ. Lv, View ORCID ProfileC. Lynch, View ORCID ProfileT.T. Mallard, M. Marcelis, R.D. Markello, View ORCID ProfileB. Mazoyer, P. McGuire, M.J. Meaney, A. Mechelli, View ORCID ProfileN. Medic, B. Misic, S.E. Morgan, D. Mothersill, J. Nigg, View ORCID ProfileM.Q.W. Ong, View ORCID ProfileC. Ortinau, View ORCID ProfileR. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, View ORCID ProfileP.M. Pan, View ORCID ProfileC. Pantelis, View ORCID ProfileM.M. Park, View ORCID ProfileT. Paus, View ORCID ProfileZ. Pausova, View ORCID ProfileA. Pichet Binette, K. Pierce, View ORCID ProfileX. Qian, View ORCID ProfileJ. Qiu, View ORCID ProfileA. Qiu, A. Raznahan, View ORCID ProfileT. Rittman, View ORCID ProfileC.K. Rollins, R. Romero-Garcia, L. Ronan, View ORCID ProfileM.D. Rosenberg, View ORCID ProfileD.H. Rowitch, View ORCID ProfileG.A. Salum, View ORCID ProfileT.D. Satterthwaite, H.L. Schaare, R.J. Schachar, View ORCID ProfileA.P. Schultz, G. Schumann, View ORCID ProfileM. Schöll, View ORCID ProfileD. Sharp, View ORCID ProfileR.T. Shinohara, View ORCID ProfileI. Skoog, C.D. Smyser, View ORCID ProfileR.A. Sperling, D.J. Stein, A. Stolicyn, J. Suckling, View ORCID ProfileG. Sullivan, View ORCID ProfileY. Taki, View ORCID ProfileB. Thyreau, View ORCID ProfileR. Toro, View ORCID ProfileK.A. Tsvetanov, N.B. Turk-Browne, View ORCID ProfileJ.J. Tuulari, View ORCID ProfileC. Tzourio, É. Vachon-Presseau, View ORCID ProfileM.J. Valdes-Sosa, View ORCID ProfileP.A. Valdes-Sosa, S.L. Valk, T. van Amelsvoort, View ORCID ProfileS.N. Vandekar, L. Vasung, View ORCID ProfileL.W. Victoria, View ORCID ProfileS. Villeneuve, A. Villringer, P.E. Vértes, View ORCID ProfileK. Wagstyl, Y.S. Wang, View ORCID ProfileS.K. Warfield, View ORCID ProfileV. Warrier, View ORCID ProfileE. Westman, View ORCID ProfileM.L. Westwater, H.C. Whalley, View ORCID ProfileA.V. Witte, N. Yang, View ORCID ProfileB.T.T. Yeo, H.J. Yun, View ORCID ProfileA. Zalesky, H.J. Zar, View ORCID ProfileA. Zettergren, View ORCID ProfileJ.H. Zhou, View ORCID ProfileH. Ziauddeen, View ORCID ProfileA. Zugman, View ORCID ProfileX.N. Zuo, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, View ORCID ProfileThe PREVENT-AD Research Group, VETSA, Bullmore, E.T., View ORCID ProfileA.F. Alexander-Bloch
doi: https://doi.org/10.1101/2021.06.08.447489
R.A.I. Bethlehem
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
2Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
J. Seidlitz
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
4Department of Child and Adolescent Psychiatry and Behavioral Science, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104
S.R. White
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
6MRC Biostatistics Unit, University of Cambridge, Cambridge, England
J.W. Vogel
7Lifespan Informatics & Neuroimaging Center, University of Pennsylvania, Philadelphia, PA 19104
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
K.M. Anderson
8Department of Psychology, Yale University, New Haven, CT, USA
C. Adamson
9Developmental Imaging, Murdoch Children’s Research Institute, Melbourne, Victoria, Australia
10Department of Medicine, Monash University, Melbourne, Victoria, Australia
S. Adler
11UCL Great Ormond Street Institute for Child Health, 30 Guilford St, Holborn, London WC1N 1EH
G.S. Alexopoulos
12Weill Cornell Institute of Geriatric Psychiatry, Department of Psychiatry, Weill Cornell Medicine
E. Anagnostou
13Department of Pediatrics University of Toronto
14Holland Bloorview Kids Rehabilitation Hospital, Toronto, Canada
A. Areces-Gonzalez
15Joint China-Cuba Lab, University of Electronic Science and Technology, Chengdu China/Cuban Center for Neuroscience, La Habana, Cuba
D.E. Astle
16MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge UK
B. Auyeung
17Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, United Kingdom
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
M. Ayub
18University College London, Mental Health Neuroscience Research Department, Division of Psychiatry, London UK
G. Ball
9Developmental Imaging, Murdoch Children’s Research Institute, Melbourne, Victoria, Australia
19Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
S. Baron-Cohen
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
20Cambridge Lifetime Asperger Syndrome Service (CLASS), Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, United Kingdom
R. Beare
9Developmental Imaging, Murdoch Children’s Research Institute, Melbourne, Victoria, Australia
10Department of Medicine, Monash University, Melbourne, Victoria, Australia
S.A. Bedford
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
V. Benegal
21Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bengaluru, India 560029
F. Beyer
22Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, 04103, Germany
J. Bin Bae
23Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea
J. Blangero
24Department of Human Genetics, South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley
M. Blesa Cábez
25MRC Centre for Reproductive Health, University of Edinburgh, UK
J.P. Boardman
25MRC Centre for Reproductive Health, University of Edinburgh, UK
M. Borzage
26Fetal and Neonatal Institute, Division of Neonatology, Children’s Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California USA
J.F. Bosch-Bayard
27McGill Centre for Integrative Neuroscience, Ludmer Centre for Neuroinformatics and Mental Health, Montreal Neurological Institute
28McGill University
N. Bourke
29Department of Brain Sciences, Imperial College London, London UK & Care Research & Technology Centre, UK Dementia Research Institute
V.D. Calhoun
30Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, GA, USA
M.M. Chakravarty
31Computational Brain Anatomy (CoBrA) Laboratory, Cerebral Imaging Centre, Douglas Mental Health University Institute
28McGill University
C. Chen
32Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
C. Chertavian
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
G. Chetelat
33Normandie Univ, UNICAEN, INSERM, U1237, PhIND “Physiopathology and Imaging of Neurological Disorders”, Institut Blood and Brain @ Caen-Normandie, Cyceron, 14000 Caen, France
Y.S. Chong
34Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore
35Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
J.H. Cole
36Centre for Medical Image Computing (CMIC), University College London
37Dementia Research Centre (DRC), University College London
A. Corvin
38Department of Psychiatry, Trinity College, Dublin, Ireland
E. Courchesne
39Department of Neuroscience, University of California, San Diego, San Diego, CA 92093, USA
40Autism Center of Excellence, University of California, San Diego, San Diego, CA 92037, USA
F. Crivello
41Institute of Neurodegenerative Disorders, CNRS UMR5293, University of Bordeaux
V.L. Cropley
42Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
J. Crosbie
43The Hospital for Sick Children, Toronto, Canada
N. Crossley
44Department of Psychiatry, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, Santiago 8330077, Chile
45Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, De Crespigny Park, London SE5 8AF, UK
M. Delarue
46UNICAEN, INSERM, U1237, PhIND “Physiopathology and Imaging of Neurological Disorders”, Institut Blood and Brain & Caen-Normandie, Cyceron, 14000 Caen, France
S. Desrivieres
47Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom
G. Devenyi
48Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, QC, Canada
49Department of Psychiatry, McGill University, Montreal, QC, Canada
M.A. Di Biase
42Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
50Department of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States
R. Dolan
51Max Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, UK
52Wellcome Centre for Human Neuroimaging, University College London, London, UK
K.A. Donald
53University of Cape Town, South Africa, Cape Town, South Africa
G. Donohoe
54Center for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, National University of Ireland Galway, Galway, Ireland
K. Dunlop
55Weil Family Brain and Mind Research Institute, Department of Psychiatry, Weill Cornell Medicine
A.D. Edwards
56Centre for the Developing Brain, King’s College London, London, UK
57Evelina London Children’s Hospital
J.T. Elison
58Institute of Child Development, Department of Pediatrics, Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, United States
C.T. Ellis
8Department of Psychology, Yale University, New Haven, CT, USA
J.A. Elman
59Department of Psychiatry, Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA
L. Eyler
60Desert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare, San Diego, CA, USA
61Department of Psychiatry, University of California San Diego, Los Angeles, CA, USA
D.A. Fair
58Institute of Child Development, Department of Pediatrics, Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, United States
P.C. Fletcher
62Department of Psychiatry, University of Cambridge, and Wellcome Trust MRC Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, United Kingdom
63Cambridgeshire and Peterborough NHS Foundation Trust
P. Fonagy
64Department of Clinical, Educational and Health Psychology, University College London, London, UK
C.E. Franz
65Department of Psychiatry, Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA 92093
L. Galan-Garcia
66Cuban Center for Neuroscience, La Habana, Cuba
A. Gholipour
67Computational Radiology Laboratory, Boston Children’s Hospital, Boston, MA 02115
J. Giedd
68Department of Child and Adolescent Psychiatry, University of California, San Diego, San Diego, CA 92093, USA
J.H. Gilmore
69Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
D.C. Glahn
70Department of Psychiatry, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115
71Harvard Medical School, Boston, MA 02115
I. Goodyer
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
P.E. Grant
72Division of Newborn Medicine and Neuroradiology, Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA
N.A. Groenewold
73Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital, SA-MRC Unit on Child & Adolescent Health, University of Cape Town, South Africa
74Neuroscience Institute, University of Cape Town, Cape Town, South Africa
F.M. Gunning
12Weill Cornell Institute of Geriatric Psychiatry, Department of Psychiatry, Weill Cornell Medicine
R.E. Gur
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
75Lifespan Brain Institute, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104
R.C. Gur
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
76Lifespan Brain Institute, The Children’s Hospital of Philadelphia, Philadelphia, PA 19105
C.F. Hammill
43The Hospital for Sick Children, Toronto, Canada
77Mouse Imaging Centre, Toronto, Canada
O. Hansson
78Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden
79Memory Clinic, Skåne University Hospital, Malmö, Sweden
T. Hedden
80Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
81Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
A. Heinz
82Department of Psychiatry and Psychotherapy, Charite University Hospital Berlin, Berlin, Germany
R. Henson
16MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge UK
83Department of Psychiatry, University of Cambridge, Cambridge, UK
K. Heuer
84Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
85Université de Paris, Paris, France
J. Hoare
86Department of Psychiatry, University of Cape Town, Cape Town, South Africa
B. Holla
87Departments of Psychiatry and Integrative Medicine, NIMHANS, Bengaluru, India
A.J. Holmes
88Departments of Psychology and Psychiatry, Yale University, New Haven, CT, USA
R. Holt
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
H. Huang
89Radiology Research, Children’s Hospital of Philadelphia, Philadelphia, United States
90The Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States
K. Im
91Division of Newborn Medicine, Fetal Neonatal Neuroimaging and Developmental Science Center, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA
92Boston Children’s Hospital, Boston, MA 02115
J. Ipser
93Department of Psychiatry and Mental Health, Clinical Neuroscience Institute, University of Cape Town
C.R. Jack Jr
94Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
A.P. Jackowski
95Department of Psychiatry, Universidade Federal de São Paulo
96National Institute of Developmental Psychiatry, CNPq
T. Jia
97Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, 200433, China
98Key Laboratory of Computational Neuroscience and BrainInspired Intelligence (Fudan University), Ministry of Education, Shanghai, China
99Centre for Population Neuroscience and Precision Medicine (PONS), Institute of Psychiatry, Psychology and Neuroscience, SGDP Centre, King’s College London, London SE5 8AF, UK
K.A. Johnson
100Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114
101Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women’s Hospital, Boston, MA 02115
71Harvard Medical School, Boston, MA 02115
P.B. Jones
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
103Cambridgeshire and Peterborough NHS Foundation Trust, Huntingdon, United Kingdom
D.T. Jones
104Department of Neurology, Mayo Clinic, Rochester, MN, USA
105Department of Radiology, Mayo Clinic, Rochester, MN, USA
R. Kahn
106Department of Psychiatry Division of Neurosciences, University Medical Center, Utrecht, The Netherlands
107Department of Psychiatry, Icahn School of Medicine, Mount Sinai, New York, USA
H. Karlsson
108Department of Clinical Medicine, Department of Psychiatry and Turku Brain and Mind Center, FinnBrain Birth Cohort Study, University of Turku and Turku University Hospital, Turku, Finland
109Centre for Population Health Research, Turku University Hospital and University of Turku, Turku, Finland
110Turku Brain and Mind Center, Department of Clinical Medicine
L. Karlsson
108Department of Clinical Medicine, Department of Psychiatry and Turku Brain and Mind Center, FinnBrain Birth Cohort Study, University of Turku and Turku University Hospital, Turku, Finland
109Centre for Population Health Research, Turku University Hospital and University of Turku, Turku, Finland
110Turku Brain and Mind Center, Department of Clinical Medicine
R. Kawashima
111Institute of Development, Aging and Cancer, Tohoku University, Seiryocho, Aobaku, Sendai 980-8575, Japan
E.A. Kelley
112Queen’s University, Department of Psychology, Centre for Neuroscience Studies, Kingston, Ontario, Canada
S. Kern
113Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
K. Kim
114Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Republic of Korea
115Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
116Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
M.G. Kitzbichler
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
W.S. Kremen
59Department of Psychiatry, Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA
F. Lalonde
117Section on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, MD, USA
B. Landeau
33Normandie Univ, UNICAEN, INSERM, U1237, PhIND “Physiopathology and Imaging of Neurological Disorders”, Institut Blood and Brain @ Caen-Normandie, Cyceron, 14000 Caen, France
S. Lee
118Department of Brain & Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Korea
J. Lerch
119Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
120Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada
121Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK
J.D. Lewis
122Montreal Neurological Institute, McGill University, Montreal, Canada
J. Li
123The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu 611731, China
W. Liao
123The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu 611731, China
D.P. Linares
15Joint China-Cuba Lab, University of Electronic Science and Technology, Chengdu China/Cuban Center for Neuroscience, La Habana, Cuba
C. Liston
124Department of Psychiatry and Brain and Mind Research Institute, Weill Cornell Medicine
M.V. Lombardo
125Laboratory for Autism and Neurodevelopmental Disorders, Center for Neuroscience and Cognitive Systems @UniTn, Istituto Italiano di Tecnologia, Rovereto, Italy
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
J. Lv
42Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
126School of Biomedical Engineering & Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia
C. Lynch
55Weil Family Brain and Mind Research Institute, Department of Psychiatry, Weill Cornell Medicine
T.T. Mallard
127Department of Psychology, University of Texas, Austin, Texas 78712, USA
M. Marcelis
128Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, EURON, Maastricht University Medical Centre, PO Box 616, 6200 MD, Maastricht, the Netherlands; Institute for Mental Health Care Eindhoven (GGzE), Eindhoven, the Netherlands
R.D. Markello
129McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
B. Mazoyer
41Institute of Neurodegenerative Disorders, CNRS UMR5293, University of Bordeaux
130Bordeaux University Hospital
P. McGuire
131Professor, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK
M.J. Meaney
132Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada; Singapore Institute for Clinical Sciences, Singapore
A. Mechelli
131Professor, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK
N. Medic
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
B. Misic
129McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
S.E. Morgan
133Department of Computer Science and Technology, University of Cambridge, Cambridge CB3 0FD, United Kingdom
134Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom
135The Alan Turing Institute, London, NW1 2DB
D. Mothersill
136Department of Psychology, School of Business, National College of Ireland, Dublin, Ireland
137School of Psychology & Center for Neuroimaging and Cognitive Genomics, National University of Ireland Galway, Galway, Ireland
138Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
J. Nigg
139Department of Psychiatry, School of Medicine, Oregon Health and Science University, Portland, United States
M.Q.W. Ong
140Center for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
C. Ortinau
141Department of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, United States
R. Ossenkoppele
142Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
143Lund University, Clinical Memory Research Unit, Lund, Sweden
M. Ouyang
89Radiology Research, Children’s Hospital of Philadelphia, Philadelphia, United States
L. Palaniyappan
144Robarts Research Institute & The Brain and Mind Institute, University of Western Ontario, London, Ontario, Canada
L. Paly
145INSERM, U1237, PhIND “Physiopathology and Imaging of Neurological Disorders”, Institut Blood and Brain @ Caen-Normandie, Cyceron, 14000 Caen, France
P.M. Pan
146Department of Psychiatry, Federal University of Sao Poalo (UNIFESP)
147National Institute of Developmental Psychiatry for Children and Adolescents (INPD), Brazil
C. Pantelis
148Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria, Australia
149Melbourne School of Engineering, The University of Melbourne, Parkville, Victoria, Australia
150Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia
M.M. Park
151Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
T. Paus
152Department of Psychiatry, Faculty of Medicine and Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Quebec, Canada
153Departments of Psychiatry and Psychology, University of Toronto, Toronto, ON, Canada
Z. Pausova
43The Hospital for Sick Children, Toronto, Canada
154Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Canada
A. Pichet Binette
155Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Qc, H3A 1Y2, Canada
156Douglas Mental Health University Institute, Montreal, Qc, H4H 1R3, Canada
K. Pierce
157Autism Center of Excellence, Department of Neurosciences, University of California, San Diego La Jolla, CA, USA
X. Qian
140Center for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
J. Qiu
158School of Psychology, Southwest University, Chongqing 400715, P.R. China
A. Qiu
159Department of Biomedical Engineering, The N.1 Institute for Health, National University of Singapore
A. Raznahan
117Section on Developmental Neurogenomics, Human Genetics Branch, National Institute of Mental Health, Bethesda, MD, USA
T. Rittman
160Department of Clinical Neurosciences, University of Cambridge, Cambridge UK
C.K. Rollins
161Department of Neurology, Harvard Medical School
162Department of Neurology, Boston Children’s Hospital, Boston, MA 02115
R. Romero-Garcia
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
L. Ronan
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
M.D. Rosenberg
163Department of Psychology, Neuroscience Institute, University of Chicago
D.H. Rowitch
164Department of Paediatrics and Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Hills Road, Cambridge, UK
G.A. Salum
165Department of Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS)
166National Institute of Developmental Psychiatry (INPD)
T.D. Satterthwaite
7Lifespan Informatics & Neuroimaging Center, University of Pennsylvania, Philadelphia, PA 19104
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
H.L. Schaare
167Otto Hahn Group Cognitive Neurogenetics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
168Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Juelich, Juelich, Germany
R.J. Schachar
43The Hospital for Sick Children, Toronto, Canada
A.P. Schultz
100Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114
169Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
71Harvard Medical School, Boston, MA 02115
G. Schumann
170Centre for Population Neuroscience and Stratified Medicine (PONS), SGDP Centre, IoPPN, KCL, UK
171PONS-Centre, Dept of Psychiatry and Psychotherapy, Campus Charite Mitte, Humboldt University, Berlin, Germany
172PONS Centre, Institute for Science and Technology of Brain-inspired Intelligence (ISTBI), Fudan University, Shanghai, China
M. Schöll
173Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
174Department of Psychiatry and Neurochemistry, University of Gothenburg, Sweden
175Dementia Research Centre, Queen’s Square Institute of Neurology, University College London, UK
D. Sharp
29Department of Brain Sciences, Imperial College London, London UK & Care Research & Technology Centre, UK Dementia Research Institute
R.T. Shinohara
32Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
176Center for Biomedical Image Computing and Analytics, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
I. Skoog
113Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
C.D. Smyser
177Departments of Neurology, Pediatrics, and Radiology, Washington University School of Medicine, St. Louis, United States
R.A. Sperling
100Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114
101Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women’s Hospital, Boston, MA 02115
71Harvard Medical School, Boston, MA 02115
D.J. Stein
178SA MRC Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa
A. Stolicyn
179Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, UK
J. Suckling
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
G. Sullivan
25MRC Centre for Reproductive Health, University of Edinburgh, UK
Y. Taki
111Institute of Development, Aging and Cancer, Tohoku University, Seiryocho, Aobaku, Sendai 980-8575, Japan
B. Thyreau
111Institute of Development, Aging and Cancer, Tohoku University, Seiryocho, Aobaku, Sendai 980-8575, Japan
R. Toro
180Department of Neuroscience, Institut Pasteur, Paris, France
85Université de Paris, Paris, France
K.A. Tsvetanov
160Department of Clinical Neurosciences, University of Cambridge, Cambridge UK
181Department of Psychology, University of Cambridge, Cambridge, UK
N.B. Turk-Browne
8Department of Psychology, Yale University, New Haven, CT, USA
182Wu Tsai Institute, Yale University, New Haven, CT, USA
J.J. Tuulari
183Department of Psychiatry, University of Turku, Turku Finland
184Department of Clinical Medicine, University of Turku, Turku Finland
185Turku Collegium for Science, Medicine and Technology, University of Turku, Turku, Finland
C. Tzourio
186Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, U1219, CHU Bordeaux, F-33000 Bordeaux, France
É. Vachon-Presseau
187Department of Anesthesia, Faculty of Medicine, McGill University, Montreal, Qc, H3A 1G1, Canada
188Faculty of Dentistry, McGill University, Montreal, Qc, H3A 1G1, Canada
189Alan Edwards Centre for Research on Pain (AECRP), McGill University, Montreal, Qc, H3A 1G1, Canada
M.J. Valdes-Sosa
66Cuban Center for Neuroscience, La Habana, Cuba
P.A. Valdes-Sosa
15Joint China-Cuba Lab, University of Electronic Science and Technology, Chengdu China/Cuban Center for Neuroscience, La Habana, Cuba
190University of Electronic Science and Technology of China/Cuban Center for Neuroscience
S.L. Valk
191Institute for Neuroscience and Medicine 7, Forschungszentrum Juelich; Max Planck Institute for Human Cognitive and Brain Sciences
T. van Amelsvoort
192Department of Psychiatry & Neurosychology, Maastricht University, Maastricht, The Netherlands
S.N. Vandekar
193Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA
194Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA
L. Vasung
195Division of Newborn Medicine, Fetal Neonatal Neuroimaging and Developmental Science Center, Department of Pediatrics, Boston Children’s Hospital, Boston, MA 02115
L.W. Victoria
12Weill Cornell Institute of Geriatric Psychiatry, Department of Psychiatry, Weill Cornell Medicine
S. Villeneuve
156Douglas Mental Health University Institute, Montreal, Qc, H4H 1R3, Canada
196McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
155Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Qc, H3A 1Y2, Canada
A. Villringer
22Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, 04103, Germany
197Clinic for Cognitive Neurology, University of Leipzig Medical Center, Leipzig, 04103, Germany
P.E. Vértes
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
198The Alan Turing Institute, London NW1 2DB, UK
K. Wagstyl
199Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3AR
Y.S. Wang
200State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
201Research Center for Lifespan Development of Brain and Mind, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
202National Basic Science Data Center, Chinese Academy of Sciences, Beijing, China
S.K. Warfield
67Computational Radiology Laboratory, Boston Children’s Hospital, Boston, MA 02115
V. Warrier
1Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
E. Westman
204Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
M.L. Westwater
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
H.C. Whalley
179Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, UK
A.V. Witte
197Clinic for Cognitive Neurology, University of Leipzig Medical Center, Leipzig, 04103, Germany
22Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, 04103, Germany
205Faculty of Medicine, CRC 1052 ‘Obesity Mechanisms’, University of Leipzig, Leipzig, 04103, Germany
N. Yang
200State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
201Research Center for Lifespan Development of Brain and Mind, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
206National Basic Science Data Center, Chinese Academy of Sciences, Beijing 100190, China
B.T.T. Yeo
207Department of Electrical and Computer Engineering, National University of Singapore, Singapore
208Centre for Sleep & Cognition and Centre for Translational MR Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
209N.1 Institute for Health & Institute for Digital Medicine, National University of Singapore, Singapore
H.J. Yun
211Fetal Neonatal Neuroimaging and Developmental Science Center, Division of Newborn Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA
A. Zalesky
212Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia; Department of Biomedical Engineering, University of Melbourne, Melbourne, Australia
H.J. Zar
73Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital, SA-MRC Unit on Child & Adolescent Health, University of Cape Town, South Africa
213SAMRC Unit on Child & Adolescent Health, University of Cape Town, South Africa
A. Zettergren
113Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
J.H. Zhou
140Center for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
214Center for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
207Department of Electrical and Computer Engineering, National University of Singapore, Singapore
H. Ziauddeen
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
215Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0SZ
216Cambridgeshire and Peterborough Foundation Trust, Cambridge, CB21 5EF
A. Zugman
217National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland, USA
218Department of Psychiatry, Escola Paulista de Medicina, São Paulo, Brazil
X.N. Zuo
200State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
201Research Center for Lifespan Development of Brain and Mind, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
206National Basic Science Data Center, Chinese Academy of Sciences, Beijing 100190, China
5Department of Psychiatry, University of Cambridge, Cambridge, CB2 0SZ, UK
A.F. Alexander-Bloch
3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104
4Department of Child and Adolescent Psychiatry and Behavioral Science, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104
Abstract
Over the past 25 years, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, there are no reference standards against which to anchor measures of individual differences in brain morphology, in contrast to growth charts for traits such as height and weight. Here, we built an interactive online resource (www.brainchart.io) to quantify individual differences in brain structure from any current or future magnetic resonance imaging (MRI) study, against models of expected age-related trends. With the goal of basing these on the largest and most inclusive dataset, we aggregated MRI data spanning 115 days post-conception through 100 postnatal years, totaling 122,123 scans from 100,071 individuals in over 100 studies across 6 continents. When quantified as centile scores relative to the reference models, individual differences show high validity with non-MRI brain growth estimates and high stability across longitudinal assessment. Centile scores helped identify previously unreported brain developmental milestones and demonstrated increased genetic heritability compared to non-centiled MRI phenotypes. Crucially for the study of brain disorders, centile scores provide a standardised and interpretable measure of deviation that reveals new patterns of neuroanatomical differences across neurological and psychiatric disorders emerging during development and ageing. In sum, brain charts for the human lifespan are an essential first step towards robust, standardised quantification of individual variation and for characterizing deviation from age-related trends. Our global collaborative study provides such an anchorpoint for basic neuroimaging research and will facilitate implementation of research-based standards in clinical studies.
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
↵* Data used in the preparation of this article was obtained from the Australian Imaging Biomarkers and Lifestyle flagship study of ageing (AIBL) funded by the Commonwealth Scientific and Industrial Research Organisation (CSIRO) which was made available at the ADNI database (https://www.loni.usc.edu/ADNI). The AIBL researchers contributed data but did not participate in analysis or writing of this report. AIBL researchers are listed at https://www.aibl.csiro.au.
↵** Data used in preparation of this article were obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing of ADNI investigators can be found at: http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdf
↵*** A complete listing of ARWiBo researchers can be found in the Supplementary Materials
↵**** The Centre for Attention Learning and Memory (CALM) research clinic is based at and supported by funding from the Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, as well as funding from the EU Horizon 2020 Personalised Medicine “LifeBrain” project (H2020-SC1-2016-2017, Topic SC1-PM-04-2016). The lead investigators are Duncan Astle, Kate Baker, Susan E. Gathercole, Joni Holmes, Rogier A. Kievit, and Tom Manly. Data collection was assisted by a team of researchers and PhD students that includes Danyla Akarca, Joe Bathelt, Giacomo Bignardi, Sarah Bishop, Erica Botanic, Lara Bridge, Diandra Bkric, Annie Bryant, Sally Butterfield, Elizabeth Byrne, Gemma Crickmore, Edwin Dalmaijer; Fánchea Daly, Tina Emery, Grace Franckel, Laura Forde, Delia Fuhrmann, Andrew Gadie, Sara Gharooni, Jacalyn Guy, Erin Hawkins, Agniezska Jaroslawska, Sara Joeghan, Amy Johnson, Jonathan Jones, Elise Ng-Cordell, Sinéad O’Brien, Cliodhna O’Leary, Joseph Rennie, Ivan Simpson-Kent, Roma Siugzdaite, Tess Smith, Stepheni Uh, Francesca Woolgar, Mengya Zhang, and Natalia Zdorovtsova. We thank the many professionals working in children’s services in the southeast and east of England for their support and to the children and their families for giving up their time to visit the clinic, and the radiographer for facilitating pediatric scanning.
↵***** The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) research was supported by the Biotechnology and Biological Sciences Research Council (BB/H008217/1), as well as funding from the Medical Research Council Cognition and Brain Sciences Unit, and the EU Horizon 2020 Personalised Medicine “LifeBrain” project (H2020-SC1-2016-2017, Topic SC1-PM-04-2016). We thank the Cam-CAN respondents and their primary care teams in Cambridge for their participation in this study. Further information about the Cam-CAN corporate authorship membership can be found at http://www.cam-can.org/index.php?content=corpauth#12.
↵****** Data used in this article were obtained from the developmental component ‘Growing Up in China’ and the standardization component ‘3R-BRAIN’ of Chinese Color Nest Project (https://github.com/zuoxinian/CCNP). More information of the CCNP team can be found at the DeepNeuro Lab (http://deepneuro.bnu.edu.cn/?p=163).
↵******* Data was downloaded from the COllaborative Informatics and Neuroimaging Suite Data Exchange tool (COINS; http://coins.mrn.org/dx) and data collection was performed at the Mind Research Network, and funded by a Center of Biomedical Research Excellence (COBRE) grant 5P20RR021938/P20GM103472 from the NIH to Dr. Vince Calhoun.
↵******** The ENIGMA Developmental Brain Age working group principally consists of Drs. James Cole, Niall Bourke, Heather Whalley, David Glahn, Laura Han, Francesca Biondo, Katherine Karlsgodt, Carrie Bearden, Jakob Seidlitz, Richard Bethlehem, Eileen Xu, Marieke Bos, Sam Mathia, Sophia Frangou, Miruna Carmen Barbu, Yoonho Chung, and Aaron Alexander-Bloch
↵********* Data used in the preparation of this article were obtained from the Harvard Aging Brain Study (HABS - P01AG036694; https://habs.mgh.harvard.edu). The HABS study was launched in 2010, funded by the National Institute on Aging. and is led by principal investigators Reisa A. Sperling MD and Keith A. Johnson MD at Massachusetts General Hospital/Harvard Medical School in Boston, MA.
↵********** Data used in this article were obtained from the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) (https://recode.re.kr).
↵*********** A full list of NSPN consortium members can be found at: https://www.nspn.org.uk/nspn-team/
↵************ The POND network is a Canadian translational network in neurodevelopmental disorders, primarily funded by the Ontario Brain Institute.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Posted June 10, 2021.
Brain charts for the human lifespan
R.A.I. Bethlehem, J. Seidlitz, S.R. White, J.W. Vogel, K.M. Anderson, C. Adamson, S. Adler, G.S. Alexopoulos, E. Anagnostou, A. Areces-Gonzalez, D.E. Astle, B. Auyeung, M. Ayub, G. Ball, S. Baron-Cohen, R. Beare, S.A. Bedford, V. Benegal, F. Beyer, J. Bin Bae, J. Blangero, M. Blesa Cábez, J.P. Boardman, M. Borzage, J.F. Bosch-Bayard, N. Bourke, V.D. Calhoun, M.M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y.S. Chong, J.H. Cole, A. Corvin, E. Courchesne, F. Crivello, V.L. Cropley, J. Crosbie, N. Crossley, M. Delarue, S. Desrivieres, G. Devenyi, M.A. Di Biase, R. Dolan, K.A. Donald, G. Donohoe, K. Dunlop, A.D. Edwards, J.T. Elison, C.T. Ellis, J.A. Elman, L. Eyler, D.A. Fair, P.C. Fletcher, P. Fonagy, C.E. Franz, L. Galan-Garcia, A. Gholipour, J. Giedd, J.H. Gilmore, D.C. Glahn, I. Goodyer, P.E. Grant, N.A. Groenewold, F.M. Gunning, R.E. Gur, R.C. Gur, C.F. Hammill, O. Hansson, T. Hedden, A. Heinz, R. Henson, K. Heuer, J. Hoare, B. Holla, A.J. Holmes, R. Holt, H. Huang, K. Im, J. Ipser, C.R. Jack Jr, A.P. Jackowski, T. Jia, K.A. Johnson, P.B. Jones, D.T. Jones, R. Kahn, H. Karlsson, L. Karlsson, R. Kawashima, E.A. Kelley, S. Kern, K. Kim, M.G. Kitzbichler, W.S. Kremen, F. Lalonde, B. Landeau, S. Lee, J. Lerch, J.D. Lewis, J. Li, W. Liao, D.P. Linares, C. Liston, M.V. Lombardo, J. Lv, C. Lynch, T.T. Mallard, M. Marcelis, R.D. Markello, B. Mazoyer, P. McGuire, M.J. Meaney, A. Mechelli, N. Medic, B. Misic, S.E. Morgan, D. Mothersill, J. Nigg, M.Q.W. Ong, C. Ortinau, R. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, P.M. Pan, C. Pantelis, M.M. Park, T. Paus, Z. Pausova, A. Pichet Binette, K. Pierce, X. Qian, J. Qiu, A. Qiu, A. Raznahan, T. Rittman, C.K. Rollins, R. Romero-Garcia, L. Ronan, M.D. Rosenberg, D.H. Rowitch, G.A. Salum, T.D. Satterthwaite, H.L. Schaare, R.J. Schachar, A.P. Schultz, G. Schumann, M. Schöll, D. Sharp, R.T. Shinohara, I. Skoog, C.D. Smyser, R.A. Sperling, D.J. Stein, A. Stolicyn, J. Suckling, G. Sullivan, Y. Taki, B. Thyreau, R. Toro, K.A. Tsvetanov, N.B. Turk-Browne, J.J. Tuulari, C. Tzourio, É. Vachon-Presseau, M.J. Valdes-Sosa, P.A. Valdes-Sosa, S.L. Valk, T. van Amelsvoort, S.N. Vandekar, L. Vasung, L.W. Victoria, S. Villeneuve, A. Villringer, P.E. Vértes, K. Wagstyl, Y.S. Wang, S.K. Warfield, V. Warrier, E. Westman, M.L. Westwater, H.C. Whalley, A.V. Witte, N. Yang, B.T.T. Yeo, H.J. Yun, A. Zalesky, H.J. Zar, A. Zettergren, J.H. Zhou, H. Ziauddeen, A. Zugman, X.N. Zuo, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, The PREVENT-AD Research Group, VETSA, Bullmore, E.T., A.F. Alexander-Bloch
bioRxiv 2021.06.08.447489; doi: https://doi.org/10.1101/2021.06.08.447489
Brain charts for the human lifespan
R.A.I. Bethlehem, J. Seidlitz, S.R. White, J.W. Vogel, K.M. Anderson, C. Adamson, S. Adler, G.S. Alexopoulos, E. Anagnostou, A. Areces-Gonzalez, D.E. Astle, B. Auyeung, M. Ayub, G. Ball, S. Baron-Cohen, R. Beare, S.A. Bedford, V. Benegal, F. Beyer, J. Bin Bae, J. Blangero, M. Blesa Cábez, J.P. Boardman, M. Borzage, J.F. Bosch-Bayard, N. Bourke, V.D. Calhoun, M.M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y.S. Chong, J.H. Cole, A. Corvin, E. Courchesne, F. Crivello, V.L. Cropley, J. Crosbie, N. Crossley, M. Delarue, S. Desrivieres, G. Devenyi, M.A. Di Biase, R. Dolan, K.A. Donald, G. Donohoe, K. Dunlop, A.D. Edwards, J.T. Elison, C.T. Ellis, J.A. Elman, L. Eyler, D.A. Fair, P.C. Fletcher, P. Fonagy, C.E. Franz, L. Galan-Garcia, A. Gholipour, J. Giedd, J.H. Gilmore, D.C. Glahn, I. Goodyer, P.E. Grant, N.A. Groenewold, F.M. Gunning, R.E. Gur, R.C. Gur, C.F. Hammill, O. Hansson, T. Hedden, A. Heinz, R. Henson, K. Heuer, J. Hoare, B. Holla, A.J. Holmes, R. Holt, H. Huang, K. Im, J. Ipser, C.R. Jack Jr, A.P. Jackowski, T. Jia, K.A. Johnson, P.B. Jones, D.T. Jones, R. Kahn, H. Karlsson, L. Karlsson, R. Kawashima, E.A. Kelley, S. Kern, K. Kim, M.G. Kitzbichler, W.S. Kremen, F. Lalonde, B. Landeau, S. Lee, J. Lerch, J.D. Lewis, J. Li, W. Liao, D.P. Linares, C. Liston, M.V. Lombardo, J. Lv, C. Lynch, T.T. Mallard, M. Marcelis, R.D. Markello, B. Mazoyer, P. McGuire, M.J. Meaney, A. Mechelli, N. Medic, B. Misic, S.E. Morgan, D. Mothersill, J. Nigg, M.Q.W. Ong, C. Ortinau, R. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, P.M. Pan, C. Pantelis, M.M. Park, T. Paus, Z. Pausova, A. Pichet Binette, K. Pierce, X. Qian, J. Qiu, A. Qiu, A. Raznahan, T. Rittman, C.K. Rollins, R. Romero-Garcia, L. Ronan, M.D. Rosenberg, D.H. Rowitch, G.A. Salum, T.D. Satterthwaite, H.L. Schaare, R.J. Schachar, A.P. Schultz, G. Schumann, M. Schöll, D. Sharp, R.T. Shinohara, I. Skoog, C.D. Smyser, R.A. Sperling, D.J. Stein, A. Stolicyn, J. Suckling, G. Sullivan, Y. Taki, B. Thyreau, R. Toro, K.A. Tsvetanov, N.B. Turk-Browne, J.J. Tuulari, C. Tzourio, É. Vachon-Presseau, M.J. Valdes-Sosa, P.A. Valdes-Sosa, S.L. Valk, T. van Amelsvoort, S.N. Vandekar, L. Vasung, L.W. Victoria, S. Villeneuve, A. Villringer, P.E. Vértes, K. Wagstyl, Y.S. Wang, S.K. Warfield, V. Warrier, E. Westman, M.L. Westwater, H.C. Whalley, A.V. Witte, N. Yang, B.T.T. Yeo, H.J. Yun, A. Zalesky, H.J. Zar, A. Zettergren, J.H. Zhou, H. Ziauddeen, A. Zugman, X.N. Zuo, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, The PREVENT-AD Research Group, VETSA, Bullmore, E.T., A.F. Alexander-Bloch
bioRxiv 2021.06.08.447489; doi: https://doi.org/10.1101/2021.06.08.447489
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