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Myofilament Glycation in Diabetes Reduces Contractility by Inhibiting Tropomyosin Movement, is Rescued by cMyBPC Domains

Maria Papadaki, Theerachat Kampaengsri, Samantha K. Barrick, View ORCID ProfileStuart G. Campbell, Dirk von Lewinski, Peter P. Rainer, Samantha P. Harris, View ORCID ProfileMichael J. Greenberg, View ORCID ProfileJonathan A. Kirk
doi: https://doi.org/10.1101/2021.06.09.447778
Maria Papadaki
1Department of Cell and Molecular Physiology, Loyola University of Chicago, Maywood, Illinois, USA
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Theerachat Kampaengsri
1Department of Cell and Molecular Physiology, Loyola University of Chicago, Maywood, Illinois, USA
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Samantha K. Barrick
2Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, St Louis, Missouri, USA
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Stuart G. Campbell
3Department of Bioengineering, Yale University, New Haven, Connecticut, USA
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Dirk von Lewinski
4Division of Cardiology, Medical University of Graz, Graz, Austria
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Peter P. Rainer
4Division of Cardiology, Medical University of Graz, Graz, Austria
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Samantha P. Harris
5Department of Cellular and Molecular Medicine, The University of Arizona, Tucson, Arizona, USA
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Michael J. Greenberg
2Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, St Louis, Missouri, USA
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Jonathan A. Kirk
1Department of Cell and Molecular Physiology, Loyola University of Chicago, Maywood, Illinois, USA
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  • ORCID record for Jonathan A. Kirk
  • For correspondence: jkirk2@luc.edu
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Posted June 09, 2021.
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Myofilament Glycation in Diabetes Reduces Contractility by Inhibiting Tropomyosin Movement, is Rescued by cMyBPC Domains
Maria Papadaki, Theerachat Kampaengsri, Samantha K. Barrick, Stuart G. Campbell, Dirk von Lewinski, Peter P. Rainer, Samantha P. Harris, Michael J. Greenberg, Jonathan A. Kirk
bioRxiv 2021.06.09.447778; doi: https://doi.org/10.1101/2021.06.09.447778
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Myofilament Glycation in Diabetes Reduces Contractility by Inhibiting Tropomyosin Movement, is Rescued by cMyBPC Domains
Maria Papadaki, Theerachat Kampaengsri, Samantha K. Barrick, Stuart G. Campbell, Dirk von Lewinski, Peter P. Rainer, Samantha P. Harris, Michael J. Greenberg, Jonathan A. Kirk
bioRxiv 2021.06.09.447778; doi: https://doi.org/10.1101/2021.06.09.447778

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