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Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimer formation and enzymatic function

View ORCID ProfileYashwanth Ashok, Carlos Vela-Rodriguez, Chunsong Yang, Heli I. Alanen, Fan Liu, View ORCID ProfileBryce M. Paschal, View ORCID ProfileLari Lehtiö
doi: https://doi.org/10.1101/2021.06.14.448324
Yashwanth Ashok
1Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Finland
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Carlos Vela-Rodriguez
1Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Finland
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Chunsong Yang
2Department of Biochemistry and Molecular genetics, University of Virginia, PO Box 800577, Charlottesville, VA22908, USA
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Heli I. Alanen
1Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Finland
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Fan Liu
3Department of Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Deutschland
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Bryce M. Paschal
2Department of Biochemistry and Molecular genetics, University of Virginia, PO Box 800577, Charlottesville, VA22908, USA
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Lari Lehtiö
1Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Finland
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  • For correspondence: lari.lehtio@oulu.fi
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Posted October 13, 2021.
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Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimer formation and enzymatic function
Yashwanth Ashok, Carlos Vela-Rodriguez, Chunsong Yang, Heli I. Alanen, Fan Liu, Bryce M. Paschal, Lari Lehtiö
bioRxiv 2021.06.14.448324; doi: https://doi.org/10.1101/2021.06.14.448324
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Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimer formation and enzymatic function
Yashwanth Ashok, Carlos Vela-Rodriguez, Chunsong Yang, Heli I. Alanen, Fan Liu, Bryce M. Paschal, Lari Lehtiö
bioRxiv 2021.06.14.448324; doi: https://doi.org/10.1101/2021.06.14.448324

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