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Tumor PD-L1 selectively suppresses type I interferon in myeloid cells to suppress CTL recruitment to promote lung metastasis
John D. Klement, Priscilla S. Redd, Chunwan Lu, Alyssa D. Merting, Dakota B. Poschel, Dafeng Yang, Gang Zhou, David H. Munn, Kebin Liu
doi: https://doi.org/10.1101/2021.06.18.449028
John D. Klement
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Priscilla S. Redd
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Chunwan Lu
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Alyssa D. Merting
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Dakota B. Poschel
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Dafeng Yang
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Gang Zhou
2Georgia Cancer Center, Augusta, GA 30912, USA
David H. Munn
2Georgia Cancer Center, Augusta, GA 30912, USA
Kebin Liu
1Department of Biochemistry and Molecular Biology, Medical College of Georgia. Augusta, GA 30912, USA
2Georgia Cancer Center, Augusta, GA 30912, USA
3Charlie Norwood VA Medical Center, Augusta, GA 30904, USA
Article usage
Posted June 18, 2021.
Tumor PD-L1 selectively suppresses type I interferon in myeloid cells to suppress CTL recruitment to promote lung metastasis
John D. Klement, Priscilla S. Redd, Chunwan Lu, Alyssa D. Merting, Dakota B. Poschel, Dafeng Yang, Gang Zhou, David H. Munn, Kebin Liu
bioRxiv 2021.06.18.449028; doi: https://doi.org/10.1101/2021.06.18.449028
Tumor PD-L1 selectively suppresses type I interferon in myeloid cells to suppress CTL recruitment to promote lung metastasis
John D. Klement, Priscilla S. Redd, Chunwan Lu, Alyssa D. Merting, Dakota B. Poschel, Dafeng Yang, Gang Zhou, David H. Munn, Kebin Liu
bioRxiv 2021.06.18.449028; doi: https://doi.org/10.1101/2021.06.18.449028
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