Hyperactive WNT/CTNNB1 signaling induces a competing cell proliferation and epidermal differentiation response in the mouse mammary epithelium

Larissa Mourao; Amber L. Zeeman; Katrin E. Wiese; Anika Bongaarts; Lieve L. Oudejans; Isabel Mora Martinez; Yorick B.C. van de Grift; Jos Jonkers; Renée van Amerongen

doi:10.1101/2021.06.22.449461

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doi

https://doi.org/10.1101/2021.06.22.449461

History

June 22, 2021.

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

Larissa Mourao#,*,1,
Amber L. Zeeman#,*,
Katrin E. Wiese#,
Anika Bongaarts#,2,
Lieve L. Oudejans#,
Isabel Mora Martinez#,
Yorick B.C. van de Grift#,
Jos Jonkers## and
Renée van Amerongen#^

^#Developmental, Stem Cell and Cancer Biology, Swammerdam Institute for Life Sciences, University of Amsterdam, Postbus 1212, 1000 BE, Amsterdam, the Netherlands
^##Oncode Institute and Division of Molecular Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands

↵^ corresponding author: r.vanamerongen{at}uva.nl

↵* equal contribution

↵1 Laboratory for Intravital Imaging and Dynamics of Tumor Progression, VIB Center for Cancer Biology, KU Leuven, Leuven, Belgium; Department of Oncology, KU Leuven, Leuven, Belgium.
↵2 Department of (Neuro)Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands