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Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from optimization of single-chain properties

View ORCID ProfileGiulio Tesei, View ORCID ProfileThea K. Schulze, View ORCID ProfileRamon Crehuet, View ORCID ProfileKresten Lindorff-Larsen
doi: https://doi.org/10.1101/2021.06.23.449550
Giulio Tesei
aStructural Biology and NMR Laboratory & the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark
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  • For correspondence: giulio.tesei@bio.ku.dk lindorff@bio.ku.dk
Thea K. Schulze
aStructural Biology and NMR Laboratory & the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark
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Ramon Crehuet
aStructural Biology and NMR Laboratory & the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark
bCSIC-Institute for Advanced Chemistry of Catalonia (IQAC), Barcelona, Spain
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Kresten Lindorff-Larsen
aStructural Biology and NMR Laboratory & the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark
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  • For correspondence: giulio.tesei@bio.ku.dk lindorff@bio.ku.dk
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Article Information

doi 
https://doi.org/10.1101/2021.06.23.449550
History 
  • September 10, 2021.

Article Versions

  • Version 1 (June 23, 2021 - 18:49).
  • Version 2 (July 23, 2021 - 08:38).
  • You are viewing Version 3, the most recent version of this article.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Giulio Teseia,1,
  2. Thea K. Schulzea,
  3. Ramon Crehueta,b and
  4. Kresten Lindorff-Larsena,1
  1. aStructural Biology and NMR Laboratory & the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark
  2. bCSIC-Institute for Advanced Chemistry of Catalonia (IQAC), Barcelona, Spain
  1. ↵1To whom correspondence should be addressed. E-mail: giulio.tesei{at}bio.ku.dk (G.T.) & lindorff{at}bio.ku.dk (K.L.-L.)
  1. Author contributions: G.T., T.K.S, R.C., and K.L.-L. designed research; G.T. and T.K.S. performed research; G.T. and R.C. developed software; G.T. and T.K.S. performed molecular simulations.; G.T. and T.K.S. analyzed data; G.T. and K.L.-L. wrote the paper with input from T.K.S and R.C.

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Posted September 10, 2021.
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Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from optimization of single-chain properties
Giulio Tesei, Thea K. Schulze, Ramon Crehuet, Kresten Lindorff-Larsen
bioRxiv 2021.06.23.449550; doi: https://doi.org/10.1101/2021.06.23.449550
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Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from optimization of single-chain properties
Giulio Tesei, Thea K. Schulze, Ramon Crehuet, Kresten Lindorff-Larsen
bioRxiv 2021.06.23.449550; doi: https://doi.org/10.1101/2021.06.23.449550

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