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The histone chaperone FACT facilitates heterochromatin spreading through regulation of histone turnover and H3K9 methylation states

View ORCID ProfileMagdalena Murawska, R. A. Greenstein, View ORCID ProfileTamas Schauer, Karl C.F. Olsen, Henry Ng, View ORCID ProfileAndreas G. Ladurner, View ORCID ProfileBassem Al-Sady, View ORCID ProfileSigurd Braun
doi: https://doi.org/10.1101/2021.06.30.450523
Magdalena Murawska
1Biomedical Center, Physiological Chemistry, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
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  • ORCID record for Magdalena Murawska
  • For correspondence: magdalena.murawska@bmc.med.lmu.de bassem.al-sady@ucsf.edu sigurd.braun@bmc.med.lmu.de
R. A. Greenstein
2Department of Microbiology and Immunology and the George Williams Hooper Foundation, University of California San Francisco, San Francisco CA 94143, United States
3TETRAD graduate program, University of California San Francisco, San Francisco CA 94143, United States
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Tamas Schauer
4Biomedical Center, Bioinformatics Unit, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
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  • ORCID record for Tamas Schauer
Karl C.F. Olsen
1Biomedical Center, Physiological Chemistry, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
5International Max Planck Research School for Molecular and Cellular Life Sciences, Planegg-Martinsried, Germany
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Henry Ng
2Department of Microbiology and Immunology and the George Williams Hooper Foundation, University of California San Francisco, San Francisco CA 94143, United States
3TETRAD graduate program, University of California San Francisco, San Francisco CA 94143, United States
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Andreas G. Ladurner
1Biomedical Center, Physiological Chemistry, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
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  • ORCID record for Andreas G. Ladurner
Bassem Al-Sady
2Department of Microbiology and Immunology and the George Williams Hooper Foundation, University of California San Francisco, San Francisco CA 94143, United States
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  • For correspondence: magdalena.murawska@bmc.med.lmu.de bassem.al-sady@ucsf.edu sigurd.braun@bmc.med.lmu.de
Sigurd Braun
1Biomedical Center, Physiological Chemistry, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
5International Max Planck Research School for Molecular and Cellular Life Sciences, Planegg-Martinsried, Germany
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  • For correspondence: magdalena.murawska@bmc.med.lmu.de bassem.al-sady@ucsf.edu sigurd.braun@bmc.med.lmu.de
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Article Information

doi 
https://doi.org/10.1101/2021.06.30.450523
History 
  • July 1, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Magdalena Murawska1,*,
  2. R. A. Greenstein2,3,
  3. Tamas Schauer4,
  4. Karl C.F. Olsen1,5,
  5. Henry Ng2,3,
  6. Andreas G. Ladurner1,
  7. Bassem Al-Sady2,* and
  8. Sigurd Braun1,5,6,*
  1. 1Biomedical Center, Physiological Chemistry, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
  2. 2Department of Microbiology and Immunology and the George Williams Hooper Foundation, University of California San Francisco, San Francisco CA 94143, United States
  3. 3TETRAD graduate program, University of California San Francisco, San Francisco CA 94143, United States
  4. 4Biomedical Center, Bioinformatics Unit, Ludwig-Maximilians-University of Munich, 82152 Planegg-Martinsried, Germany
  5. 5International Max Planck Research School for Molecular and Cellular Life Sciences, Planegg-Martinsried, Germany
  1. ↵*Correspondence: magdalena.murawska{at}bmc.med.lmu.de (M.M.), bassem.al-sady{at}ucsf.edu (B. A-S.), sigurd.braun{at}bmc.med.lmu.de (S.B.)
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Posted July 01, 2021.
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The histone chaperone FACT facilitates heterochromatin spreading through regulation of histone turnover and H3K9 methylation states
Magdalena Murawska, R. A. Greenstein, Tamas Schauer, Karl C.F. Olsen, Henry Ng, Andreas G. Ladurner, Bassem Al-Sady, Sigurd Braun
bioRxiv 2021.06.30.450523; doi: https://doi.org/10.1101/2021.06.30.450523
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The histone chaperone FACT facilitates heterochromatin spreading through regulation of histone turnover and H3K9 methylation states
Magdalena Murawska, R. A. Greenstein, Tamas Schauer, Karl C.F. Olsen, Henry Ng, Andreas G. Ladurner, Bassem Al-Sady, Sigurd Braun
bioRxiv 2021.06.30.450523; doi: https://doi.org/10.1101/2021.06.30.450523

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