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Single-cell profiling of the human primary motor cortex in ALS and FTLD
View ORCID ProfileS. Sebastian Pineda, Hyeseung Lee, View ORCID ProfileBrent E. Fitzwalter, View ORCID ProfileShahin Mohammadi, Luc J. Pregent, Mahammad E. Gardashli, Julio Mantero, View ORCID ProfileErica Engelberg-Cook, Mariely DeJesus-Hernandez, View ORCID ProfileMarka van Blitterswijk, View ORCID ProfileCyril Pottier, Rosa Rademakers, Bjorn Oskarsson, Jaimin S. Shah, Ronald C. Petersen, View ORCID ProfileNeill R. Graff-Radford, Bradley F. Boeve, David S. Knopman, Keith A. Josephs, Michael DeTure, View ORCID ProfileMelissa E. Murray, Dennis W. Dickson, Myriam Heiman, Veronique V. Belzil, Manolis Kellis
doi: https://doi.org/10.1101/2021.07.07.451374
S. Sebastian Pineda
1Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, USA
2MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
4Picower Institute for Learning and Memory, Cambridge, MA, USA
Hyeseung Lee
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
4Picower Institute for Learning and Memory, Cambridge, MA, USA
Brent E. Fitzwalter
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
4Picower Institute for Learning and Memory, Cambridge, MA, USA
Shahin Mohammadi
2MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
10Insitro Inc. South San Francisco, CA, USA
Luc J. Pregent
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Mahammad E. Gardashli
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Julio Mantero
2MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA
Erica Engelberg-Cook
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Mariely DeJesus-Hernandez
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Marka van Blitterswijk
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Cyril Pottier
6VIB Center for Molecular Neurology, VIB, Antwerp, Belgium
7Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
Rosa Rademakers
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
6VIB Center for Molecular Neurology, VIB, Antwerp, Belgium
7Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
Bjorn Oskarsson
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Jaimin S. Shah
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Ronald C. Petersen
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Neill R. Graff-Radford
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Bradley F. Boeve
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
David S. Knopman
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Keith A. Josephs
8Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA
Michael DeTure
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Melissa E. Murray
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Dennis W. Dickson
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Myriam Heiman
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
4Picower Institute for Learning and Memory, Cambridge, MA, USA
9Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA
Veronique V. Belzil
5Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
Manolis Kellis
1Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, USA
2MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA
3Broad Institute of MIT and Harvard, Cambridge, MA, USA
Article usage
Posted July 10, 2021.
Single-cell profiling of the human primary motor cortex in ALS and FTLD
S. Sebastian Pineda, Hyeseung Lee, Brent E. Fitzwalter, Shahin Mohammadi, Luc J. Pregent, Mahammad E. Gardashli, Julio Mantero, Erica Engelberg-Cook, Mariely DeJesus-Hernandez, Marka van Blitterswijk, Cyril Pottier, Rosa Rademakers, Bjorn Oskarsson, Jaimin S. Shah, Ronald C. Petersen, Neill R. Graff-Radford, Bradley F. Boeve, David S. Knopman, Keith A. Josephs, Michael DeTure, Melissa E. Murray, Dennis W. Dickson, Myriam Heiman, Veronique V. Belzil, Manolis Kellis
bioRxiv 2021.07.07.451374; doi: https://doi.org/10.1101/2021.07.07.451374
Single-cell profiling of the human primary motor cortex in ALS and FTLD
S. Sebastian Pineda, Hyeseung Lee, Brent E. Fitzwalter, Shahin Mohammadi, Luc J. Pregent, Mahammad E. Gardashli, Julio Mantero, Erica Engelberg-Cook, Mariely DeJesus-Hernandez, Marka van Blitterswijk, Cyril Pottier, Rosa Rademakers, Bjorn Oskarsson, Jaimin S. Shah, Ronald C. Petersen, Neill R. Graff-Radford, Bradley F. Boeve, David S. Knopman, Keith A. Josephs, Michael DeTure, Melissa E. Murray, Dennis W. Dickson, Myriam Heiman, Veronique V. Belzil, Manolis Kellis
bioRxiv 2021.07.07.451374; doi: https://doi.org/10.1101/2021.07.07.451374
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