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Cryo-EM structure of alpha-synuclein fibrils amplified by PMCA from PD and MSA patient brains

Domenic Burger, Alexis Fenyi, Luc Bousset, Henning Stahlberg, Ronald Melki
doi: https://doi.org/10.1101/2021.07.08.451588
Domenic Burger
1Laboratory of Biological Electron Microscopy, IPHYS, SB, EPFL, 1015 Lausanne, Switzerland
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Alexis Fenyi
2Institut François Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France
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Luc Bousset
2Institut François Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France
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  • For correspondence: luc.bousset@cnrs.fr henning.stahlberg@epfl.ch ronald.melki@cnrs.fr
Henning Stahlberg
1Laboratory of Biological Electron Microscopy, IPHYS, SB, EPFL, 1015 Lausanne, Switzerland
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  • For correspondence: luc.bousset@cnrs.fr henning.stahlberg@epfl.ch ronald.melki@cnrs.fr
Ronald Melki
2Institut François Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France
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  • For correspondence: luc.bousset@cnrs.fr henning.stahlberg@epfl.ch ronald.melki@cnrs.fr
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Article Information

doi 
https://doi.org/10.1101/2021.07.08.451588
History 
  • July 9, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Domenic Burger1,a,
  2. Alexis Fenyi2,a,
  3. Luc Bousset2,b,
  4. Henning Stahlberg1,b and
  5. Ronald Melki2,b
  1. 1Laboratory of Biological Electron Microscopy, IPHYS, SB, EPFL, 1015 Lausanne, Switzerland
  2. 2Institut François Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France
  1. ↵bCorrespondence to: Luc Bousset (luc.bousset{at}cnrs.fr), Henning Stahlberg (henning.stahlberg{at}epfl.ch) and Ronald Melki (ronald.melki{at}cnrs.fr).
  1. ↵a Contributed equally

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Posted July 09, 2021.
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Cryo-EM structure of alpha-synuclein fibrils amplified by PMCA from PD and MSA patient brains
Domenic Burger, Alexis Fenyi, Luc Bousset, Henning Stahlberg, Ronald Melki
bioRxiv 2021.07.08.451588; doi: https://doi.org/10.1101/2021.07.08.451588
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Cryo-EM structure of alpha-synuclein fibrils amplified by PMCA from PD and MSA patient brains
Domenic Burger, Alexis Fenyi, Luc Bousset, Henning Stahlberg, Ronald Melki
bioRxiv 2021.07.08.451588; doi: https://doi.org/10.1101/2021.07.08.451588

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