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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
View ORCID ProfileAnna Osnato, Stephanie Brown, View ORCID ProfileChristel Krueger, View ORCID ProfileSimon Andrews, View ORCID ProfileAmanda J. Collier, Shota Nakanoh, Mariana Quiroga Londoño, View ORCID ProfileBrandon T. Wesley, Daniele Muraro, Sophie Brumm, View ORCID ProfileKathy Niakan, View ORCID ProfileLudovic Vallier, Daniel Ortmann, View ORCID ProfilePeter J. Rugg-Gunn
doi: https://doi.org/10.1101/2021.07.10.451887
Anna Osnato
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Stephanie Brown
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Christel Krueger
3Bioinformatics Group, The Babraham Institute, Cambridge, CB22 3AT, UK
Simon Andrews
3Bioinformatics Group, The Babraham Institute, Cambridge, CB22 3AT, UK
Amanda J. Collier
4Epigenetics Programme, The Babraham Institute, Cambridge, CB22 3AT, UK
Shota Nakanoh
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
5Division of Embryology, National Institute for Basic Biology, Okazaki 444-8787, Japan
Mariana Quiroga Londoño
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Brandon T. Wesley
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Daniele Muraro
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
6Wellcome Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
Sophie Brumm
7Human Embryo and Stem Cell Laboratory, The Francis Crick Institute, London, NW1 1AT, UK
Kathy Niakan
7Human Embryo and Stem Cell Laboratory, The Francis Crick Institute, London, NW1 1AT, UK
8Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK
Ludovic Vallier
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Daniel Ortmann
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
2Department of Surgery, University of Cambridge, Cambridge, CB2 0SZ, UK
Peter J. Rugg-Gunn
1Wellcome–MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK
4Epigenetics Programme, The Babraham Institute, Cambridge, CB22 3AT, UK
8Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK
Article usage
Posted July 11, 2021.
TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
Anna Osnato, Stephanie Brown, Christel Krueger, Simon Andrews, Amanda J. Collier, Shota Nakanoh, Mariana Quiroga Londoño, Brandon T. Wesley, Daniele Muraro, Sophie Brumm, Kathy Niakan, Ludovic Vallier, Daniel Ortmann, Peter J. Rugg-Gunn
bioRxiv 2021.07.10.451887; doi: https://doi.org/10.1101/2021.07.10.451887
TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
Anna Osnato, Stephanie Brown, Christel Krueger, Simon Andrews, Amanda J. Collier, Shota Nakanoh, Mariana Quiroga Londoño, Brandon T. Wesley, Daniele Muraro, Sophie Brumm, Kathy Niakan, Ludovic Vallier, Daniel Ortmann, Peter J. Rugg-Gunn
bioRxiv 2021.07.10.451887; doi: https://doi.org/10.1101/2021.07.10.451887
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