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Autofluorescence microscopy as a label-free tool for renal histology and glomerular segmentation

View ORCID ProfileNathan Heath Patterson, View ORCID ProfileElizabeth K. Neumann, View ORCID ProfileKavya Sharman, Jamie Allen, View ORCID ProfileRaymond Harris, View ORCID ProfileAgnes B. Fogo, View ORCID ProfileMark de Caestecker, View ORCID ProfileRichard M. Caprioli, View ORCID ProfileRaf Van de Plas, View ORCID ProfileJeffrey M. Spraggins
doi: https://doi.org/10.1101/2021.07.16.452703
Nathan Heath Patterson
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
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  • ORCID record for Nathan Heath Patterson
Elizabeth K. Neumann
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
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Kavya Sharman
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
3Program in Chemical and Physical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
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Jamie Allen
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
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Raymond Harris
5Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN USA 37232
6Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN USA 37232
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Agnes B. Fogo
7Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN USA 37232
8Department of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN USA 37232
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  • ORCID record for Agnes B. Fogo
Mark de Caestecker
9Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN USA 37232
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  • ORCID record for Mark de Caestecker
Richard M. Caprioli
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
4Department of Chemistry, Vanderbilt University, Nashville, TN, USA 37232
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Raf Van de Plas
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
9Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN USA 37232
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Jeffrey M. Spraggins
1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
4Department of Chemistry, Vanderbilt University, Nashville, TN, USA 37232
11Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN USA 37232
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  • ORCID record for Jeffrey M. Spraggins
  • For correspondence: jeff.spraggins@vanderbilt.edu
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Article Information

doi 
https://doi.org/10.1101/2021.07.16.452703
History 
  • July 18, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Nathan Heath Patterson1,2,
  2. Elizabeth K. Neumann1,2,
  3. Kavya Sharman1,2,3,
  4. Jamie Allen1,2,
  5. Raymond Harris5,6,
  6. Agnes B. Fogo7,8,
  7. Mark de Caestecker9,
  8. Richard M. Caprioli1,2,4,
  9. Raf Van de Plas1,2,9 and
  10. Jeffrey M. Spraggins1,2,4,11,*
  1. 1Department of Biochemistry, Vanderbilt University, Nashville, TN, USA 37232
  2. 2Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA 37232
  3. 3Program in Chemical and Physical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
  4. 4Department of Chemistry, Vanderbilt University, Nashville, TN, USA 37232
  5. 5Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN USA 37232
  6. 6Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN USA 37232
  7. 7Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN USA 37232
  8. 8Department of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN USA 37232
  9. 9Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN USA 37232
  10. 10Delft Center for Systems and Control, Delft University of Technology, Delft, Netherlands
  11. 11Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN USA 37232
  1. ↵*Corresponding author: jeff.spraggins{at}vanderbilt.edu
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Posted July 18, 2021.
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Autofluorescence microscopy as a label-free tool for renal histology and glomerular segmentation
Nathan Heath Patterson, Elizabeth K. Neumann, Kavya Sharman, Jamie Allen, Raymond Harris, Agnes B. Fogo, Mark de Caestecker, Richard M. Caprioli, Raf Van de Plas, Jeffrey M. Spraggins
bioRxiv 2021.07.16.452703; doi: https://doi.org/10.1101/2021.07.16.452703
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Autofluorescence microscopy as a label-free tool for renal histology and glomerular segmentation
Nathan Heath Patterson, Elizabeth K. Neumann, Kavya Sharman, Jamie Allen, Raymond Harris, Agnes B. Fogo, Mark de Caestecker, Richard M. Caprioli, Raf Van de Plas, Jeffrey M. Spraggins
bioRxiv 2021.07.16.452703; doi: https://doi.org/10.1101/2021.07.16.452703

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