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ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
View ORCID ProfileSenem Aykul, Lily Huang, Lili Wang, Nanditha Das, Sandra Reisman, Yonaton Ray, Qian Zhang, View ORCID ProfileNyanza Rothman, View ORCID ProfileKalyan C. Nannuru, View ORCID ProfileVishal Kamat, View ORCID ProfileSusannah Brydges, View ORCID ProfileLuca Troncone, Laura Johnsen, View ORCID ProfilePaul B. Yu, View ORCID ProfileJohn Lees-Shepard, Kevin Schutz, Andrew J. Murphy, View ORCID ProfileAris N. Economides, View ORCID ProfileVincent Idone, Sarah J. Hatsell
doi: https://doi.org/10.1101/2021.07.18.452865
Senem Aykul
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Lily Huang
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Lili Wang
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Nanditha Das
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Sandra Reisman
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Yonaton Ray
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Qian Zhang
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Nyanza Rothman
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Kalyan C. Nannuru
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Vishal Kamat
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Susannah Brydges
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Luca Troncone
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02114, USA
Laura Johnsen
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Paul B. Yu
2Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02114, USA
John Lees-Shepard
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Kevin Schutz
3Adimab, 7 Lucent Dr, Lebanon, NH 03766, USA
Andrew J. Murphy
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Aris N. Economides
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Vincent Idone
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Sarah J. Hatsell
1Regeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA
Article usage
Posted July 19, 2021.
ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
Senem Aykul, Lily Huang, Lili Wang, Nanditha Das, Sandra Reisman, Yonaton Ray, Qian Zhang, Nyanza Rothman, Kalyan C. Nannuru, Vishal Kamat, Susannah Brydges, Luca Troncone, Laura Johnsen, Paul B. Yu, John Lees-Shepard, Kevin Schutz, Andrew J. Murphy, Aris N. Economides, Vincent Idone, Sarah J. Hatsell
bioRxiv 2021.07.18.452865; doi: https://doi.org/10.1101/2021.07.18.452865
ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
Senem Aykul, Lily Huang, Lili Wang, Nanditha Das, Sandra Reisman, Yonaton Ray, Qian Zhang, Nyanza Rothman, Kalyan C. Nannuru, Vishal Kamat, Susannah Brydges, Luca Troncone, Laura Johnsen, Paul B. Yu, John Lees-Shepard, Kevin Schutz, Andrew J. Murphy, Aris N. Economides, Vincent Idone, Sarah J. Hatsell
bioRxiv 2021.07.18.452865; doi: https://doi.org/10.1101/2021.07.18.452865
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