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GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers
Dong Yan Zhang, Jian Wang, Rebecca M. Fleeman, Madison K. Kuhn, Matthew T. Swulius, Elizabeth A. Proctor, View ORCID ProfileNikolay V. Dokholyan
doi: https://doi.org/10.1101/2021.07.22.453392
Dong Yan Zhang
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
Jian Wang
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
Rebecca M. Fleeman
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
2Department of Neurosurgery, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
3Center for Neural Engineering, Pennsylvania State University, University Park, PA
Madison K. Kuhn
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
2Department of Neurosurgery, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
3Center for Neural Engineering, Pennsylvania State University, University Park, PA
4Department of Biomedical Engineering, Pennsylvania State University, University Park, PA
Matthew T. Swulius
6Departments of Biochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
Elizabeth A. Proctor
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
2Department of Neurosurgery, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
3Center for Neural Engineering, Pennsylvania State University, University Park, PA
4Department of Biomedical Engineering, Pennsylvania State University, University Park, PA
5Department of Engineering Science & Mechanics, Pennsylvania State University, University Park, PA
Nikolay V. Dokholyan
1Department of Pharmacology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
4Department of Biomedical Engineering, Pennsylvania State University, University Park, PA
6Departments of Biochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA, 17033-0850, USA
7Department of Chemistry, Pennsylvania State University, University Park, PA
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Posted July 22, 2021.
GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers
Dong Yan Zhang, Jian Wang, Rebecca M. Fleeman, Madison K. Kuhn, Matthew T. Swulius, Elizabeth A. Proctor, Nikolay V. Dokholyan
bioRxiv 2021.07.22.453392; doi: https://doi.org/10.1101/2021.07.22.453392
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