Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad; Yueyun Zhang; Céline Stibolt; Sendurai A. Mani; George Sflomos; Cathrin Brisken

doi:10.1101/2021.07.22.453458

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Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, Sendurai A. Mani, George Sflomos, View ORCID ProfileCathrin Brisken

doi: https://doi.org/10.1101/2021.07.22.453458

Patrick Aouad

1ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

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Yueyun Zhang

1ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

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Céline Stibolt

1ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

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Sendurai A. Mani

2Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, Texas 77030

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George Sflomos

1ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

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Cathrin Brisken

1ISREC - Swiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

3The Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK

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ORCID record for Cathrin Brisken
For correspondence: cathrin.brisken@epfl.ch

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Posted July 26, 2021.

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Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, Sendurai A. Mani, George Sflomos, Cathrin Brisken

bioRxiv 2021.07.22.453458; doi: https://doi.org/10.1101/2021.07.22.453458

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Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, Sendurai A. Mani, George Sflomos, Cathrin Brisken

bioRxiv 2021.07.22.453458; doi: https://doi.org/10.1101/2021.07.22.453458

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