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A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae
Paulina Kaplonek, Ling Yao, Katrin Reppe, Franziska Voß, Thomas Kohler, Friederike Ebner, Alexander Schäfer, Ulrike Blohm, Patricia Priegue, Maria Bräutigam, Claney L. Pereira, Sharavathi G. Parameswarappa, Madhu Emmadi, Petra Ménová, Martin Witzenrath, Sven Hammerschmidt, Susanne Hartmann, Leif E. Sander, Peter H. Seeberger
doi: https://doi.org/10.1101/2021.07.29.454378
Paulina Kaplonek
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
2Freie Universität Berlin, Institute of Chemistry and Biochemistry, Arnimallee 22, 14195 Berlin, Germany
#Ragon Institute of MGH, MIT, and Harvard, 400 Technology Square, Cambridge, 02139 MA, USA
Ling Yao
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
3Department of Infectious Diseases and Respiratory Medicine, Charité - Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Katrin Reppe
3Department of Infectious Diseases and Respiratory Medicine, Charité - Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Franziska Voß
4Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany
Thomas Kohler
4Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany
Friederike Ebner
5Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163 Berlin, Germany
Alexander Schäfer
6Institute of Immunology, Friedrich-Loeffler-Institut, Südufer 10, 17493 Greifswald-Insel Riems, Germany
Ulrike Blohm
6Institute of Immunology, Friedrich-Loeffler-Institut, Südufer 10, 17493 Greifswald-Insel Riems, Germany
Patricia Priegue
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
Maria Bräutigam
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
Claney L. Pereira
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
Sharavathi G. Parameswarappa
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
Madhu Emmadi
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
Petra Ménová
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
†University of Chemistry and Technology, Prague, Technicka 5, 166 28 Prague, Czech Republic
Martin Witzenrath
3Department of Infectious Diseases and Respiratory Medicine, Charité - Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
7German Center for Lung Research (DZL), Aulweg 130, 35392 Giessen, Germany
Sven Hammerschmidt
4Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany
Susanne Hartmann
5Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163 Berlin, Germany
Leif E. Sander
3Department of Infectious Diseases and Respiratory Medicine, Charité - Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
7German Center for Lung Research (DZL), Aulweg 130, 35392 Giessen, Germany
Peter H. Seeberger
1Max-Planck-Institute of Colloids and Interfaces, Department of Biomolecular Systems, Am Mühlenberg 1, 14476 Potsdam, Germany
2Freie Universität Berlin, Institute of Chemistry and Biochemistry, Arnimallee 22, 14195 Berlin, Germany
Article usage
Posted July 30, 2021.
A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae
Paulina Kaplonek, Ling Yao, Katrin Reppe, Franziska Voß, Thomas Kohler, Friederike Ebner, Alexander Schäfer, Ulrike Blohm, Patricia Priegue, Maria Bräutigam, Claney L. Pereira, Sharavathi G. Parameswarappa, Madhu Emmadi, Petra Ménová, Martin Witzenrath, Sven Hammerschmidt, Susanne Hartmann, Leif E. Sander, Peter H. Seeberger
bioRxiv 2021.07.29.454378; doi: https://doi.org/10.1101/2021.07.29.454378
A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae
Paulina Kaplonek, Ling Yao, Katrin Reppe, Franziska Voß, Thomas Kohler, Friederike Ebner, Alexander Schäfer, Ulrike Blohm, Patricia Priegue, Maria Bräutigam, Claney L. Pereira, Sharavathi G. Parameswarappa, Madhu Emmadi, Petra Ménová, Martin Witzenrath, Sven Hammerschmidt, Susanne Hartmann, Leif E. Sander, Peter H. Seeberger
bioRxiv 2021.07.29.454378; doi: https://doi.org/10.1101/2021.07.29.454378
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