Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Dashboard-style interactive plots for RNA-seq analysis are R Markdown ready with Glimma 2.0

Hasaru Kariyawasam, View ORCID ProfileShian Su, Oliver Voogd, View ORCID ProfileMatthew E. Ritchie, View ORCID ProfileCharity W. Law
doi: https://doi.org/10.1101/2021.07.30.454464
Hasaru Kariyawasam
1Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shian Su
1Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Shian Su
Oliver Voogd
1Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matthew E. Ritchie
1Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Australia
2Department of Medical Biology, The University of Melbourne, Parkville, Australia
3School of Mathematics and Statistics, The University of Melbourne, Parkville, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Matthew E. Ritchie
Charity W. Law
1Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Australia
2Department of Medical Biology, The University of Melbourne, Parkville, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Charity W. Law
  • For correspondence: law@wehi.edu.au
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Glimma 1.0 introduced intuitive, point-and-click interactive graphics for differential gene expression analysis. Here, we present a major update to Glimma which brings improved inter-activity and reproducibility using high-level visualisation frame-works for R and JavaScript. Glimma 2.0 plots are now readily embeddable in R Markdown, thus allowing users to create reproducible reports containing interactive graphics. The revamped multidimensional scaling plot features dashboard-style controls allowing the user to dynamically change the colour, shape and size of sample points according to different experimental conditions. Interactivity was enhanced in the MA-style plot for comparing differences to average expression, which now supports selecting multiple genes, export options to PNG, SVG or CSV formats and includes a new volcano plot function. Feature-rich and user-friendly, Glimma makes exploring data for gene expression analysis more accessible and intuitive and is available on Bioconductor and GitHub.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Back to top
PreviousNext
Posted August 01, 2021.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Dashboard-style interactive plots for RNA-seq analysis are R Markdown ready with Glimma 2.0
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Dashboard-style interactive plots for RNA-seq analysis are R Markdown ready with Glimma 2.0
Hasaru Kariyawasam, Shian Su, Oliver Voogd, Matthew E. Ritchie, Charity W. Law
bioRxiv 2021.07.30.454464; doi: https://doi.org/10.1101/2021.07.30.454464
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Dashboard-style interactive plots for RNA-seq analysis are R Markdown ready with Glimma 2.0
Hasaru Kariyawasam, Shian Su, Oliver Voogd, Matthew E. Ritchie, Charity W. Law
bioRxiv 2021.07.30.454464; doi: https://doi.org/10.1101/2021.07.30.454464

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Bioinformatics
Subject Areas
All Articles
  • Animal Behavior and Cognition (4238)
  • Biochemistry (9159)
  • Bioengineering (6797)
  • Bioinformatics (24054)
  • Biophysics (12149)
  • Cancer Biology (9564)
  • Cell Biology (13819)
  • Clinical Trials (138)
  • Developmental Biology (7654)
  • Ecology (11733)
  • Epidemiology (2066)
  • Evolutionary Biology (15536)
  • Genetics (10665)
  • Genomics (14353)
  • Immunology (9504)
  • Microbiology (22887)
  • Molecular Biology (9120)
  • Neuroscience (49094)
  • Paleontology (357)
  • Pathology (1487)
  • Pharmacology and Toxicology (2579)
  • Physiology (3851)
  • Plant Biology (8349)
  • Scientific Communication and Education (1473)
  • Synthetic Biology (2300)
  • Systems Biology (6204)
  • Zoology (1302)