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Discovery of aryl aminothiazole γ-secretase modulators with novel effects on amyloid β-peptide production
Sanjay Bhattarai, Lei Liu, Dennis J. Selkoe, View ORCID ProfileMichael S. Wolfe
doi: https://doi.org/10.1101/2021.08.09.455471
Sanjay Bhattarai
aDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045 USA
Lei Liu
bAnn Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115 USA
Dennis J. Selkoe
bAnn Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115 USA
Michael S. Wolfe
aDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045 USA
Posted August 09, 2021.
Discovery of aryl aminothiazole γ-secretase modulators with novel effects on amyloid β-peptide production
Sanjay Bhattarai, Lei Liu, Dennis J. Selkoe, Michael S. Wolfe
bioRxiv 2021.08.09.455471; doi: https://doi.org/10.1101/2021.08.09.455471
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