Single molecule fingerprinting reveals different amplification properties of α-synuclein oligomers and preformed fibrils in seeding assay

Derrick Lau; Chloé Magnan; Kathryn Hill; Antony Cooper; Yann Gambin; Emma Sierecki

doi:10.1101/2021.08.09.455607

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Single molecule fingerprinting reveals different amplification properties of α-synuclein oligomers and preformed fibrils in seeding assay

View ORCID ProfileDerrick Lau, Chloé Magnan, Kathryn Hill, View ORCID ProfileAntony Cooper, View ORCID ProfileYann Gambin, View ORCID ProfileEmma Sierecki

doi: https://doi.org/10.1101/2021.08.09.455607

Derrick Lau

1EMBL Australia Node for Single Molecule Sciences and School of Medical Sciences, Faculty of Medicine, the University of New South Wales, Sydney NSW 2052 Australia

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ORCID record for Derrick Lau

Chloé Magnan

1EMBL Australia Node for Single Molecule Sciences and School of Medical Sciences, Faculty of Medicine, the University of New South Wales, Sydney NSW 2052 Australia

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Kathryn Hill

2The Australian Parkinson’s Mission, The Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia

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Antony Cooper

2The Australian Parkinson’s Mission, The Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia

3St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia

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ORCID record for Antony Cooper
For correspondence: e.sierecki@unsw.edu.au y.gambin@unsw.edu.au a.cooper@garvan.org.au

Yann Gambin

1EMBL Australia Node for Single Molecule Sciences and School of Medical Sciences, Faculty of Medicine, the University of New South Wales, Sydney NSW 2052 Australia

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ORCID record for Yann Gambin
For correspondence: e.sierecki@unsw.edu.au y.gambin@unsw.edu.au a.cooper@garvan.org.au

Emma Sierecki

1EMBL Australia Node for Single Molecule Sciences and School of Medical Sciences, Faculty of Medicine, the University of New South Wales, Sydney NSW 2052 Australia

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ORCID record for Emma Sierecki
For correspondence: e.sierecki@unsw.edu.au y.gambin@unsw.edu.au a.cooper@garvan.org.au

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Posted August 09, 2021.

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Single molecule fingerprinting reveals different amplification properties of α-synuclein oligomers and preformed fibrils in seeding assay

Derrick Lau, Chloé Magnan, Kathryn Hill, Antony Cooper, Yann Gambin, Emma Sierecki

bioRxiv 2021.08.09.455607; doi: https://doi.org/10.1101/2021.08.09.455607

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Single molecule fingerprinting reveals different amplification properties of α-synuclein oligomers and preformed fibrils in seeding assay

Derrick Lau, Chloé Magnan, Kathryn Hill, Antony Cooper, Yann Gambin, Emma Sierecki

bioRxiv 2021.08.09.455607; doi: https://doi.org/10.1101/2021.08.09.455607

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