Abstract
Summary MiSDEED is a command-line tool for generating synthetic longitudinal multi-omics data from simulated microbial environments. It generates relative-abundance timecourses under perturbations for an arbitrary number of samples and patients. All simulation parameters are exposed to the user to facilitate rapid power analysis and aid in study design. Users who want additional flexibility may also use MiSDEED as a Python package.
Availability and implementation MiSDEED is written in Python and is freely available at https://github.com/pchlenski/misdeed.
Contact pac{at}cs.columbia.edu
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Posted August 10, 2021.
MiSDEED: a synthetic multi-omics engine for microbiome power analysis and study design
