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Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility

James Talwar, David Laub, View ORCID ProfileMeghana Pagadala, Andrea Castro, McKenna Lewis, Georg E. Luebeck, Gerald P. Morris, Rany M. Salem, Wesley K. Thompson, Kit Curtius, Maurizio Zanetti, View ORCID ProfileHannah Carter
doi: https://doi.org/10.1101/2021.08.12.456166
James Talwar
1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA
2Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA
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David Laub
1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA
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Meghana Pagadala
3Biomedical Science Program, University of California San Diego, La Jolla, CA 92093, USA
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  • ORCID record for Meghana Pagadala
Andrea Castro
1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA
2Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA
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McKenna Lewis
4Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA 92093, USA
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Georg E. Luebeck
5Public Health Sciences Division, Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
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Gerald P. Morris
6Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA
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Rany M. Salem
7Division of Epidemiology, Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA 92093, USA
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Wesley K. Thompson
8Division of Biostatistics and Department of Radiology, Population Neuroscience and Genetics Lab, University of California San Diego, La Jolla, CA 92093, USA
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Kit Curtius
2Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA
9Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA
10Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
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Maurizio Zanetti
9Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA
11The Laboratory of Immunology, University of California San Diego, La Jolla, CA 92093, USA
12Department of Medicine, Division of Hematology and Oncology, University of California San Diego, La Jolla, CA 92093, USA
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Hannah Carter
1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA
2Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA
9Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA
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  • ORCID record for Hannah Carter
  • For correspondence: hkcarter@health.ucsd.edu
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Article Information

doi 
https://doi.org/10.1101/2021.08.12.456166
History 
  • August 13, 2021.

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  • You are currently viewing Version 1 of this article (August 13, 2021 - 16:01).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. James Talwar1,2,
  2. David Laub1,
  3. Meghana Pagadala3,
  4. Andrea Castro1,2,
  5. McKenna Lewis4,
  6. Georg E. Luebeck5,
  7. Gerald P. Morris6,
  8. Rany M. Salem7,
  9. Wesley K. Thompson8,
  10. Kit Curtius2,9,10,
  11. Maurizio Zanetti9,11,12 and
  12. Hannah Carter1,2,9,*
  1. 1Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA
  2. 2Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA
  3. 3Biomedical Science Program, University of California San Diego, La Jolla, CA 92093, USA
  4. 4Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA 92093, USA
  5. 5Public Health Sciences Division, Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
  6. 6Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA
  7. 7Division of Epidemiology, Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA 92093, USA
  8. 8Division of Biostatistics and Department of Radiology, Population Neuroscience and Genetics Lab, University of California San Diego, La Jolla, CA 92093, USA
  9. 9Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA
  10. 10Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
  11. 11The Laboratory of Immunology, University of California San Diego, La Jolla, CA 92093, USA
  12. 12Department of Medicine, Division of Hematology and Oncology, University of California San Diego, La Jolla, CA 92093, USA
  1. ↵*Correspondence to:
    hkcarter{at}health.ucsd.edu
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Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility
James Talwar, David Laub, Meghana Pagadala, Andrea Castro, McKenna Lewis, Georg E. Luebeck, Gerald P. Morris, Rany M. Salem, Wesley K. Thompson, Kit Curtius, Maurizio Zanetti, Hannah Carter
bioRxiv 2021.08.12.456166; doi: https://doi.org/10.1101/2021.08.12.456166
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Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility
James Talwar, David Laub, Meghana Pagadala, Andrea Castro, McKenna Lewis, Georg E. Luebeck, Gerald P. Morris, Rany M. Salem, Wesley K. Thompson, Kit Curtius, Maurizio Zanetti, Hannah Carter
bioRxiv 2021.08.12.456166; doi: https://doi.org/10.1101/2021.08.12.456166

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