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A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913
Julia Kazmierski, Carina Elsner, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Fabian Pott, Jenny Jansen, Christian W. Thorball, Ole Zeymer, Xiaoyi Zhou, Roman Fedorov, Jacques Fellay, Markus W. Löffler, Alexander N. R. Weber, Beate Sodeik, Christine Goffinet
doi: https://doi.org/10.1101/2021.08.24.457532
Julia Kazmierski
1Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
2Berlin Institute of Health, Berlin (BIH), Anna-Louisa-Karsch-Str. 2, 10178 Berlin, Germany
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Carina Elsner
4Institute for Virology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Katinka Döhner
5Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany
Shuting Xu
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Aurélie Ducroux
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Fabian Pott
1Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
2Berlin Institute of Health, Berlin (BIH), Anna-Louisa-Karsch-Str. 2, 10178 Berlin, Germany
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Jenny Jansen
1Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
2Berlin Institute of Health, Berlin (BIH), Anna-Louisa-Karsch-Str. 2, 10178 Berlin, Germany
Christian W. Thorball
6School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
7Swiss Institute of Bioinformatics, Lausanne, Switzerland
8Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
Ole Zeymer
9Institute for Biophysical Chemistry, Research Division for Structural Biochemistry, Hannover Medical School, Hannover, Germany
Xiaoyi Zhou
9Institute for Biophysical Chemistry, Research Division for Structural Biochemistry, Hannover Medical School, Hannover, Germany
15RESIST – Cluster of Excellence, Hannover Medical School, Hannover, Germany
Roman Fedorov
9Institute for Biophysical Chemistry, Research Division for Structural Biochemistry, Hannover Medical School, Hannover, Germany
15RESIST – Cluster of Excellence, Hannover Medical School, Hannover, Germany
Jacques Fellay
6School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
7Swiss Institute of Bioinformatics, Lausanne, Switzerland
8Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
Markus W. Löffler
10Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany
11Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Tübingen Germany
12Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany
13iFIT – Cluster of Excellence (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, Tübingen, Germany
Alexander N. R. Weber
10Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany
13iFIT – Cluster of Excellence (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, Tübingen, Germany
14CMFI – Cluster of Excellence (EXC 2124) “Controlling microbes to fight infection”, University of Tübingen, Tübingen, Germany
Beate Sodeik
5Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany
15RESIST – Cluster of Excellence, Hannover Medical School, Hannover, Germany
16German Center for Infection Research (DZIF), Hannover-Braunschweig Partner site, Germany
Christine Goffinet
1Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
2Berlin Institute of Health, Berlin (BIH), Anna-Louisa-Karsch-Str. 2, 10178 Berlin, Germany
3Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany
Article usage
Posted August 25, 2021.
A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913
Julia Kazmierski, Carina Elsner, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Fabian Pott, Jenny Jansen, Christian W. Thorball, Ole Zeymer, Xiaoyi Zhou, Roman Fedorov, Jacques Fellay, Markus W. Löffler, Alexander N. R. Weber, Beate Sodeik, Christine Goffinet
bioRxiv 2021.08.24.457532; doi: https://doi.org/10.1101/2021.08.24.457532
A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913
Julia Kazmierski, Carina Elsner, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Fabian Pott, Jenny Jansen, Christian W. Thorball, Ole Zeymer, Xiaoyi Zhou, Roman Fedorov, Jacques Fellay, Markus W. Löffler, Alexander N. R. Weber, Beate Sodeik, Christine Goffinet
bioRxiv 2021.08.24.457532; doi: https://doi.org/10.1101/2021.08.24.457532
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