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Increased 20-HETE signaling suppresses neurovascular coupling after ischemic stroke in regions beyond the infarct

View ORCID ProfileZhenzhou Li, View ORCID ProfileHeather L. McConnell, View ORCID ProfileTeresa L. Stackhouse, View ORCID ProfileMartin M. Pike, View ORCID ProfileWenri Zhang, View ORCID ProfileAnusha Mishra
doi: https://doi.org/10.1101/2021.08.25.457547
Zhenzhou Li
1Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR
2Department Anesthesiology, General Hospital of Ningxia Medical University, Ningxia, China
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Heather L. McConnell
3Department of Neurology, Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, OR
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Teresa L. Stackhouse
3Department of Neurology, Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, OR
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Martin M. Pike
4Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR
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Wenri Zhang
5Department of Anesthesiology and Peri-operative Medicine, Oregon Health & Science University, Portland, OR
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Anusha Mishra
1Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR
3Department of Neurology, Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, OR
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  • For correspondence: mishraa@ohsu.edu
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Article Information

doi 
https://doi.org/10.1101/2021.08.25.457547
History 
  • August 27, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Zhenzhou Li1,2,†,
  2. Heather L. McConnell3,†,#,
  3. Teresa L. Stackhouse3,
  4. Martin M. Pike4,
  5. Wenri Zhang5 and
  6. Anusha Mishra1,3,*
  1. 1Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR
  2. 2Department Anesthesiology, General Hospital of Ningxia Medical University, Ningxia, China
  3. 3Department of Neurology, Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, OR
  4. 4Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR
  5. 5Department of Anesthesiology and Peri-operative Medicine, Oregon Health & Science University, Portland, OR
  1. ↵*Correspondence:
    mishraa{at}ohsu.edu
  1. ↵† These authors have contributed equally to this work.

  • ↵# Office of Academic Development, Houston Methodist Research Institute, Houston, TX

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Posted August 27, 2021.
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Increased 20-HETE signaling suppresses neurovascular coupling after ischemic stroke in regions beyond the infarct
Zhenzhou Li, Heather L. McConnell, Teresa L. Stackhouse, Martin M. Pike, Wenri Zhang, Anusha Mishra
bioRxiv 2021.08.25.457547; doi: https://doi.org/10.1101/2021.08.25.457547
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Increased 20-HETE signaling suppresses neurovascular coupling after ischemic stroke in regions beyond the infarct
Zhenzhou Li, Heather L. McConnell, Teresa L. Stackhouse, Martin M. Pike, Wenri Zhang, Anusha Mishra
bioRxiv 2021.08.25.457547; doi: https://doi.org/10.1101/2021.08.25.457547

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