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Structurally complex osteosarcoma genomes exhibit limited heterogeneity within individual tumors and across evolutionary time
View ORCID ProfileSanjana Rajan, View ORCID ProfileSimone Zaccaria, Matthew V. Cannon, Maren Cam, Amy C. Gross, View ORCID ProfileBenjamin J. Raphael, View ORCID ProfileRyan D. Roberts
doi: https://doi.org/10.1101/2021.08.30.458268
Sanjana Rajan
1Molecular, Cellular, and Developmental Biology Program, The Ohio State University, Columbus, Ohio, USA
2Center for Childhood Cancers and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Ohio, USA
Simone Zaccaria
3Department of Computer Science, Princeton University, Princeton, NJ, USA
4Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK
5Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Matthew V. Cannon
2Center for Childhood Cancers and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Ohio, USA
Maren Cam
2Center for Childhood Cancers and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Ohio, USA
Amy C. Gross
2Center for Childhood Cancers and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Ohio, USA
Benjamin J. Raphael
3Department of Computer Science, Princeton University, Princeton, NJ, USA
6Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA
Ryan D. Roberts
2Center for Childhood Cancers and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Ohio, USA
7The Ohio State University James Comprehensive Cancer Center, Columbus, Ohio, USA
8Division of Pediatric Hematology, Oncology, and BMT, Nationwide Children’s Hospital, Columbus, Ohio, USA
Posted January 23, 2023.
Structurally complex osteosarcoma genomes exhibit limited heterogeneity within individual tumors and across evolutionary time
Sanjana Rajan, Simone Zaccaria, Matthew V. Cannon, Maren Cam, Amy C. Gross, Benjamin J. Raphael, Ryan D. Roberts
bioRxiv 2021.08.30.458268; doi: https://doi.org/10.1101/2021.08.30.458268
Structurally complex osteosarcoma genomes exhibit limited heterogeneity within individual tumors and across evolutionary time
Sanjana Rajan, Simone Zaccaria, Matthew V. Cannon, Maren Cam, Amy C. Gross, Benjamin J. Raphael, Ryan D. Roberts
bioRxiv 2021.08.30.458268; doi: https://doi.org/10.1101/2021.08.30.458268
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