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The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs
View ORCID ProfileJan Ewald, Paul Mathias Jansen, View ORCID ProfileSascha Brunke, Davina Hiller, Christian H. Luther, View ORCID ProfileHumbert González-Díaz, Marcus T. Dittrich, André Fleißner, View ORCID ProfileBernhard Hube, View ORCID ProfileStefan Schuster, View ORCID ProfileChristoph Kaleta
doi: https://doi.org/10.1101/2021.09.05.459012
Jan Ewald
1Department of Bioinformatics, Friedrich-Schiller-Universität Jena, Germany
2Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Universität Leipzig, Germany
Paul Mathias Jansen
3Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany
Sascha Brunke
3Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany
Davina Hiller
4Institut für Mikrobiologie, Technische Universität Braunschweig, Germany
Christian H. Luther
5Department of Bioinformatics, Julius-Maximilians-Universität Würzburg, Germany
Humbert González-Díaz
6Department of Organic and Inorganic Chemistry and Basque Center for Biophysics, University of the Basque Country, UPV/EHU, Leioa, Spain
7IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
Marcus T. Dittrich
5Department of Bioinformatics, Julius-Maximilians-Universität Würzburg, Germany
8Department of Human Genetics, Julius-Maximilians-Universität Würzburg, Germany
André Fleißner
9Institut für Genetik, Technische Universität Braunschweig, Germany
Bernhard Hube
3Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany
10Institute of Microbiology, Friedrich-Schiller-Universität Jena, Germany
Stefan Schuster
1Department of Bioinformatics, Friedrich-Schiller-Universität Jena, Germany
Christoph Kaleta
11Research Group Medical Systems Biology, Christian-Albrechts-Universität zu Kiel, Germany
Article usage
Posted September 06, 2021.
The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs
Jan Ewald, Paul Mathias Jansen, Sascha Brunke, Davina Hiller, Christian H. Luther, Humbert González-Díaz, Marcus T. Dittrich, André Fleißner, Bernhard Hube, Stefan Schuster, Christoph Kaleta
bioRxiv 2021.09.05.459012; doi: https://doi.org/10.1101/2021.09.05.459012
The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs
Jan Ewald, Paul Mathias Jansen, Sascha Brunke, Davina Hiller, Christian H. Luther, Humbert González-Díaz, Marcus T. Dittrich, André Fleißner, Bernhard Hube, Stefan Schuster, Christoph Kaleta
bioRxiv 2021.09.05.459012; doi: https://doi.org/10.1101/2021.09.05.459012
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