Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis

Timucin Sezai, Vinh Nguyen, Nina Riddell, Melanie J. Murphy, Sheila G. Crewther
doi: https://doi.org/10.1101/2021.09.13.459979
Timucin Sezai
aDepartment of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, 3086, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vinh Nguyen
aDepartment of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, 3086, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nina Riddell
aDepartment of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, 3086, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Melanie J. Murphy
aDepartment of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, 3086, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sheila G. Crewther
aDepartment of Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, 3086, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: s.crewther@latrobe.edu.au
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Data/Code
  • Preview PDF
Loading

Abstract

Migraine is a poorly understood neurological disorder and a leading cause of disability in young adults. Migraines are characterized by severe pulsating unilateral headache and visual symptoms. Whether visual function is also impaired in the interictal period between migraines remains controversial. Thus, this meta-analysis investigated the evidence for altered visual function as measured electrophysiologically via pattern-reversal visual evoked potential (VEP) amplitudes and habituation in adult migraineurs with or without visual aura and control in the interictal period. Twenty-three studies were selected for random effects meta-analysis, demonstrating slightly diminished VEP amplitudes and substantially reduced habituation in the early P100 component in migraineurs without aura and with aura compared to controls. No differences were found between migraineurs with and without aura. Although heterogeneity between studies and insufficient published data for VEP latencies and the earlier N75 VEP component data was observed and require further testing, P100 anomalies may indicate abnormal functioning of the fast-conducting magnocellular visual pathway, in episodic migraineurs.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • https://osf.io/pjtxk/?view_only=5d5210e898b94458a66f5bf58d5943e2

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Back to top
PreviousNext
Posted September 15, 2021.
Download PDF

Supplementary Material

Data/Code
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis
Timucin Sezai, Vinh Nguyen, Nina Riddell, Melanie J. Murphy, Sheila G. Crewther
bioRxiv 2021.09.13.459979; doi: https://doi.org/10.1101/2021.09.13.459979
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Visual Processing During the Interictal Period Between Migraines: A Meta-Analysis
Timucin Sezai, Vinh Nguyen, Nina Riddell, Melanie J. Murphy, Sheila G. Crewther
bioRxiv 2021.09.13.459979; doi: https://doi.org/10.1101/2021.09.13.459979

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (3602)
  • Biochemistry (7569)
  • Bioengineering (5524)
  • Bioinformatics (20792)
  • Biophysics (10328)
  • Cancer Biology (7981)
  • Cell Biology (11638)
  • Clinical Trials (138)
  • Developmental Biology (6603)
  • Ecology (10202)
  • Epidemiology (2065)
  • Evolutionary Biology (13617)
  • Genetics (9541)
  • Genomics (12847)
  • Immunology (7921)
  • Microbiology (19541)
  • Molecular Biology (7657)
  • Neuroscience (42096)
  • Paleontology (308)
  • Pathology (1258)
  • Pharmacology and Toxicology (2202)
  • Physiology (3267)
  • Plant Biology (7041)
  • Scientific Communication and Education (1294)
  • Synthetic Biology (1951)
  • Systems Biology (5426)
  • Zoology (1117)