Social isolation is linked to classical risk factors of Alzheimer’s disease-related dementias

Kimia Shafighi; Sylvia Villeneuve; Pedro Rosa-Neto; AmanPreet Badhwar; Judes Poirier; Vaibhav Sharma; Yasser Iturria-Medina; Patricia P Silveira; Laurette Dube; David Glahn; Danilo Bzdok

doi:10.1101/2021.09.13.460121

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Social isolation is linked to classical risk factors of Alzheimer’s disease-related dementias

Kimia Shafighi, Sylvia Villeneuve, View ORCID ProfilePedro Rosa-Neto, AmanPreet Badhwar, Judes Poirier, Vaibhav Sharma, View ORCID ProfileYasser Iturria-Medina, Patricia P Silveira, Laurette Dube, David Glahn, Danilo Bzdok

doi: https://doi.org/10.1101/2021.09.13.460121

Kimia Shafighi

1Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada

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For correspondence: kimia.shafighi@mail.mcgill.ca

Sylvia Villeneuve

2Neurology and Neurosurgery Department, Montreal Neurological Institute (MNI), Faculty of Medicine, McGill University, Montreal, Canada

3McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada

4Department of Psychiatry, McGill University, H3A 1A1, Montreal, Quebec, Canada

5Douglas Mental Health University Institute, Studies on Prevention of Alzheimer’s Disease (StoP-AD) Centre, H4H 1R3, Montreal, Quebec, Canada

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Pedro Rosa-Neto

5Douglas Mental Health University Institute, Studies on Prevention of Alzheimer’s Disease (StoP-AD) Centre, H4H 1R3, Montreal, Quebec, Canada

6Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer’s Disease Research Unit, Montreal, Canada

7Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l’Ouest-de-l’Île-de-Montréal, Montréal, Canada

8Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Canada

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ORCID record for Pedro Rosa-Neto

AmanPreet Badhwar

9Département de pharmacologie et physiologie, Faculté de médecine, Université de Montréal, Montréal, Canada

10Centre de recherche de l’Institut universitaire de gériatrie de Montréal (CRIUGM), Montréal, Canada

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Judes Poirier

11Centre for Studies in the Prevention of Alzheimer’s Disease, Douglas Mental Health Institute, McGill University, Montreal, Canada

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Vaibhav Sharma

1Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada

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Yasser Iturria-Medina

2Neurology and Neurosurgery Department, Montreal Neurological Institute (MNI), Faculty of Medicine, McGill University, Montreal, Canada

3McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada

12Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Canada

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ORCID record for Yasser Iturria-Medina

Patricia P Silveira

4Department of Psychiatry, McGill University, H3A 1A1, Montreal, Quebec, Canada

12Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Canada

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Laurette Dube

13Desautels Faculty of Management, McGill Center for the Convergence of Health and Economics, McGill University, Montreal, QC, Canada

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David Glahn

14Tommy Fuss Center for Neuropsychiatric Disease Research, Department of Psychiatry, Boston Children’s Hospital, Boston, MA, USA

15Department of Psychiatry, Harvard Medical School, Boston, MA, USA

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Danilo Bzdok

1Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada

3McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada

16School of Computer Science, McGill University, Montreal, Canada

17Mila - Quebec Artificial Intelligence Institute, Montreal, Canada

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Social isolation is linked to classical risk factors of Alzheimer’s disease-related dementias

Kimia Shafighi, Sylvia Villeneuve, Pedro Rosa-Neto, AmanPreet Badhwar, Judes Poirier, Vaibhav Sharma, Yasser Iturria-Medina, Patricia P Silveira, Laurette Dube, David Glahn, Danilo Bzdok

bioRxiv 2021.09.13.460121; doi: https://doi.org/10.1101/2021.09.13.460121

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Social isolation is linked to classical risk factors of Alzheimer’s disease-related dementias

Kimia Shafighi, Sylvia Villeneuve, Pedro Rosa-Neto, AmanPreet Badhwar, Judes Poirier, Vaibhav Sharma, Yasser Iturria-Medina, Patricia P Silveira, Laurette Dube, David Glahn, Danilo Bzdok

bioRxiv 2021.09.13.460121; doi: https://doi.org/10.1101/2021.09.13.460121

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