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Optimizing epitope conformational ensembles using α-synuclein cyclic peptide “glycindel” scaffolds: A customized immunogen method for generating oligomer-selective antibodies for Parkinson’s disease
View ORCID ProfileShawn C.C. Hsueh, View ORCID ProfileAdekunle Aina, Andrei Yu. Roman, View ORCID ProfileNeil R. Cashman, Xubiao Peng, View ORCID ProfileSteven S. Plotkin
doi: https://doi.org/10.1101/2021.09.13.460126
Shawn C.C. Hsueh
†Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC, V6T 1Z1, Canada
Adekunle Aina
†Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC, V6T 1Z1, Canada
Andrei Yu. Roman
‡Djavad Mowafaghian Centre for Brain Health, The University of British Columbia, Vancouver, BC, V6T 2B5, Canada
Neil R. Cashman
‡Djavad Mowafaghian Centre for Brain Health, The University of British Columbia, Vancouver, BC, V6T 2B5, Canada
Xubiao Peng
†Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC, V6T 1Z1, Canada
§Center for Quantum Technology Research, School of Physics, Beijing Institute of Technology, Beijing, China 100081
Steven S. Plotkin
†Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC, V6T 1Z1, Canada
¶Genome Science and Technology Program, The University of British Columbia, Vancouver, BC, V6T 1Z1, Canada
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Posted June 24, 2022.
Optimizing epitope conformational ensembles using α-synuclein cyclic peptide “glycindel” scaffolds: A customized immunogen method for generating oligomer-selective antibodies for Parkinson’s disease
Shawn C.C. Hsueh, Adekunle Aina, Andrei Yu. Roman, Neil R. Cashman, Xubiao Peng, Steven S. Plotkin
bioRxiv 2021.09.13.460126; doi: https://doi.org/10.1101/2021.09.13.460126
Optimizing epitope conformational ensembles using α-synuclein cyclic peptide “glycindel” scaffolds: A customized immunogen method for generating oligomer-selective antibodies for Parkinson’s disease
Shawn C.C. Hsueh, Adekunle Aina, Andrei Yu. Roman, Neil R. Cashman, Xubiao Peng, Steven S. Plotkin
bioRxiv 2021.09.13.460126; doi: https://doi.org/10.1101/2021.09.13.460126
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