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SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes trough mitigation of oxidative and ER stress
Zeenat A. Shyr, Zihan Yan, Alessandro Ustione, Erin M. Egan, View ORCID ProfileMaria S. Remedi
doi: https://doi.org/10.1101/2021.09.17.460837
Zeenat A. Shyr
1Department of Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University in St. Louis, St. Louis, Missouri, 63110
3Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, St. Louis, Missouri, 63110
Zihan Yan
1Department of Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University in St. Louis, St. Louis, Missouri, 63110
3Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, St. Louis, Missouri, 63110
Alessandro Ustione
2Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, 63110
Erin M. Egan
1Department of Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University in St. Louis, St. Louis, Missouri, 63110
Maria S. Remedi
1Department of Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University in St. Louis, St. Louis, Missouri, 63110
2Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, 63110
3Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, St. Louis, Missouri, 63110
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Posted September 17, 2021.
SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes trough mitigation of oxidative and ER stress
Zeenat A. Shyr, Zihan Yan, Alessandro Ustione, Erin M. Egan, Maria S. Remedi
bioRxiv 2021.09.17.460837; doi: https://doi.org/10.1101/2021.09.17.460837
SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes trough mitigation of oxidative and ER stress
Zeenat A. Shyr, Zihan Yan, Alessandro Ustione, Erin M. Egan, Maria S. Remedi
bioRxiv 2021.09.17.460837; doi: https://doi.org/10.1101/2021.09.17.460837
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