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Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME

Zikai Zhao, Qi Li, Usama Ashraf, Mengjie Yang, Wenjing Zhu, Zheng Chen, Shengbo Cao, View ORCID ProfileJing Ye
doi: https://doi.org/10.1101/2021.09.21.461218
Zikai Zhao
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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Qi Li
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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Usama Ashraf
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
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Mengjie Yang
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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Wenjing Zhu
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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Zheng Chen
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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Shengbo Cao
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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  • For correspondence: yej@mail.hzau.edu.cn sbcao@mail.hzau.edu.cn
Jing Ye
aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
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  • ORCID record for Jing Ye
  • For correspondence: yej@mail.hzau.edu.cn sbcao@mail.hzau.edu.cn
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Article Information

doi 
https://doi.org/10.1101/2021.09.21.461218
History 
  • September 22, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Zikai Zhaoa,b,c,
  2. Qi Lia,b,c,
  3. Usama Ashrafb,
  4. Mengjie Yanga,b,c,
  5. Wenjing Zhua,b,c,
  6. Zheng Chena,b,c,
  7. Shengbo Caoa,b,c,* and
  8. Jing Yea,b,c,*
  1. aState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
  2. bKey Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
  3. cThe Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
  1. ↵*Corresponding author:
    Jing Ye Email: yej{at}mail.hzau.edu.cn and Shengbo Cao Email: sbcao{at}mail.hzau.edu.cn
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Posted September 22, 2021.
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Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME
Zikai Zhao, Qi Li, Usama Ashraf, Mengjie Yang, Wenjing Zhu, Zheng Chen, Shengbo Cao, Jing Ye
bioRxiv 2021.09.21.461218; doi: https://doi.org/10.1101/2021.09.21.461218
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Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME
Zikai Zhao, Qi Li, Usama Ashraf, Mengjie Yang, Wenjing Zhu, Zheng Chen, Shengbo Cao, Jing Ye
bioRxiv 2021.09.21.461218; doi: https://doi.org/10.1101/2021.09.21.461218

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