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Mechanical stimulation promotes enthesis injury repair by mobilizing Prx1+ cells via ciliary TGF-β signaling
Han Xiao, Tao Zhang, Changjun Li, Yong Cao, Linfeng Wang, Huabin Chen, Shengcan Li, Changbiao Guan, Jianzhong Hu, Di Chen, Can Chen, View ORCID ProfileHongbin Lu
doi: https://doi.org/10.1101/2021.09.21.461317
Han Xiao
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Tao Zhang
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Changjun Li
5Department of Endocrinology, Xiangya Hospital, Central South University, Changsha 410008, China
Yong Cao
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
6Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Linfeng Wang
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Huabin Chen
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Shengcan Li
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Changbiao Guan
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
Jianzhong Hu
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
6Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Di Chen
7Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Can Chen
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
7Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Hongbin Lu
1Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008, China
2Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha 410008, China
3Xiangya Hospital-International Chinese Musculoskeletal Research Society Sports Medicine Research Centre, Changsha 410008, China
4Hunan Engineering Research Center of Sport and Health, Changsha 410008, China
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Posted September 22, 2021.
Mechanical stimulation promotes enthesis injury repair by mobilizing Prx1+ cells via ciliary TGF-β signaling
Han Xiao, Tao Zhang, Changjun Li, Yong Cao, Linfeng Wang, Huabin Chen, Shengcan Li, Changbiao Guan, Jianzhong Hu, Di Chen, Can Chen, Hongbin Lu
bioRxiv 2021.09.21.461317; doi: https://doi.org/10.1101/2021.09.21.461317
Mechanical stimulation promotes enthesis injury repair by mobilizing Prx1+ cells via ciliary TGF-β signaling
Han Xiao, Tao Zhang, Changjun Li, Yong Cao, Linfeng Wang, Huabin Chen, Shengcan Li, Changbiao Guan, Jianzhong Hu, Di Chen, Can Chen, Hongbin Lu
bioRxiv 2021.09.21.461317; doi: https://doi.org/10.1101/2021.09.21.461317
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