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TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Amit A. Upadhyay, Timothy N. Hoang, Maria Pino, Arun K. Boddapati, Elise G. Viox, Michelle Y.H. Lee, Jacqueline Corry, Zachary Strongin, David A. Cowan, Elizabeth N. Beagle, Tristan R. Horton, Sydney Hamilton, Hadj Aoued, Justin L. Harper, Kevin Nguyen, Kathryn L. Pellegrini, Gregory K. Tharp, Anne Piantadosi, Rebecca D. Levit, View ORCID ProfileRama R. Amara, Simon M. Barratt-Boyes, Susan P. Ribeiro, Rafick P. Sekaly, Thomas H. Vanderford, Raymond F. Schinazi, Mirko Paiardini, Steven E. Bosinger
doi: https://doi.org/10.1101/2021.10.05.463212
Amit A. Upadhyay
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Timothy N. Hoang
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Maria Pino
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Arun K. Boddapati
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Elise G. Viox
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Michelle Y.H. Lee
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Jacqueline Corry
3Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Zachary Strongin
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
David A. Cowan
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Elizabeth N. Beagle
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Tristan R. Horton
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Sydney Hamilton
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Hadj Aoued
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Justin L. Harper
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Kevin Nguyen
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Kathryn L. Pellegrini
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Gregory K. Tharp
2Yerkes Genomics Core Laboratory, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Anne Piantadosi
4Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Rebecca D. Levit
5Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Rama R. Amara
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
6Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, Georgia, USA
Simon M. Barratt-Boyes
3Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
7Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Susan P. Ribeiro
4Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Rafick P. Sekaly
4Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Thomas H. Vanderford
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
Raymond F. Schinazi
8Department of Pediatrics, School of Medicine, Emory University and Children’s Healthcare of Atlanta, Atlanta, Georgia, USA
Mirko Paiardini
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
4Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Steven E. Bosinger
1Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
4Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA
Article usage
Posted October 05, 2021.
TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Amit A. Upadhyay, Timothy N. Hoang, Maria Pino, Arun K. Boddapati, Elise G. Viox, Michelle Y.H. Lee, Jacqueline Corry, Zachary Strongin, David A. Cowan, Elizabeth N. Beagle, Tristan R. Horton, Sydney Hamilton, Hadj Aoued, Justin L. Harper, Kevin Nguyen, Kathryn L. Pellegrini, Gregory K. Tharp, Anne Piantadosi, Rebecca D. Levit, Rama R. Amara, Simon M. Barratt-Boyes, Susan P. Ribeiro, Rafick P. Sekaly, Thomas H. Vanderford, Raymond F. Schinazi, Mirko Paiardini, Steven E. Bosinger
bioRxiv 2021.10.05.463212; doi: https://doi.org/10.1101/2021.10.05.463212
TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Amit A. Upadhyay, Timothy N. Hoang, Maria Pino, Arun K. Boddapati, Elise G. Viox, Michelle Y.H. Lee, Jacqueline Corry, Zachary Strongin, David A. Cowan, Elizabeth N. Beagle, Tristan R. Horton, Sydney Hamilton, Hadj Aoued, Justin L. Harper, Kevin Nguyen, Kathryn L. Pellegrini, Gregory K. Tharp, Anne Piantadosi, Rebecca D. Levit, Rama R. Amara, Simon M. Barratt-Boyes, Susan P. Ribeiro, Rafick P. Sekaly, Thomas H. Vanderford, Raymond F. Schinazi, Mirko Paiardini, Steven E. Bosinger
bioRxiv 2021.10.05.463212; doi: https://doi.org/10.1101/2021.10.05.463212
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