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MetaScore: A novel machine-learning based approach to improve traditional scoring functions for scoring protein-protein docking conformations

Yong Jung, Cunliang Geng, Alexandre M. J. J. Bonvin, Li C. Xue, Vasant G. Honavar
doi: https://doi.org/10.1101/2021.10.06.463442
Yong Jung
1Bioinformatics & Genomics Graduate Program, Pennsylvania State University, University Park, PA 16802, USA
2Artificial Intelligence Research Laboratory, Pennsylvania State University, University Park, PA 16802, USA
5Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
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Cunliang Geng
8Bijvoet Centre for Biomolecular Research, Faculty of Science - Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands
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Alexandre M. J. J. Bonvin
8Bijvoet Centre for Biomolecular Research, Faculty of Science - Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands
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Li C. Xue
8Bijvoet Centre for Biomolecular Research, Faculty of Science - Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands
9Center for Molecular and Biomolecular Informatics, Radboudumc, Greet Grooteplein 26-28, 6525 GA Nijmegen, the Netherlands
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  • For correspondence: vhonavar@psu.edu Li.Xue@radboudumc.nl
Vasant G. Honavar
1Bioinformatics & Genomics Graduate Program, Pennsylvania State University, University Park, PA 16802, USA
2Artificial Intelligence Research Laboratory, Pennsylvania State University, University Park, PA 16802, USA
3Center for Big Data Analytics and Discovery Informatics, Pennsylvania State University, University Park, PA 16823, USA
4Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA 16802, USA
5Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
6Clinical and Translational Sciences Institute, Pennsylvania State University, University Park, PA 16802, USA
7College of Information Sciences & Technology, Pennsylvania State University, University Park, PA 16802, USA
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  • For correspondence: vhonavar@psu.edu Li.Xue@radboudumc.nl
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Posted October 09, 2021.
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MetaScore: A novel machine-learning based approach to improve traditional scoring functions for scoring protein-protein docking conformations
Yong Jung, Cunliang Geng, Alexandre M. J. J. Bonvin, Li C. Xue, Vasant G. Honavar
bioRxiv 2021.10.06.463442; doi: https://doi.org/10.1101/2021.10.06.463442
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MetaScore: A novel machine-learning based approach to improve traditional scoring functions for scoring protein-protein docking conformations
Yong Jung, Cunliang Geng, Alexandre M. J. J. Bonvin, Li C. Xue, Vasant G. Honavar
bioRxiv 2021.10.06.463442; doi: https://doi.org/10.1101/2021.10.06.463442

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