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Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus
View ORCID ProfileYusuke Takeshima, View ORCID ProfileYukiko Iwasaki, Masahiro Nakano, Yuta Narushima, Mineto Ota, Yasuo Nagafuchi, Shuji Sumitomo, Tomohisa Okamura, Keith B Elkon, Kazuyoshi Ishigaki, Akari Suzuki, Yuta Kochi, Kazuhiko Yamamoto, Keishi Fujio
doi: https://doi.org/10.1101/2021.10.08.463629
Yusuke Takeshima
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
2Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Yukiko Iwasaki
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
3Department of Palliative Medicine, Faculty of Medicine, Saitama Medical University, Saitama, Japan. 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan
Masahiro Nakano
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Yuta Narushima
4Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan
Mineto Ota
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
2Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Yasuo Nagafuchi
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
2Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Shuji Sumitomo
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Tomohisa Okamura
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
2Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Keith B Elkon
5Division of Rheumatology, University of Washington, WA 98109, USA
Kazuyoshi Ishigaki
6Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan
Akari Suzuki
6Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan
Yuta Kochi
6Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan
7Department of Genomic Function and Diversity, Tokyo Medical and Dental University, Tokyo 113-8150, Japan
Kazuhiko Yamamoto
6Laboratory for Autoimmune Diseases, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan
Keishi Fujio
1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan
Posted October 09, 2021.
Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus
Yusuke Takeshima, Yukiko Iwasaki, Masahiro Nakano, Yuta Narushima, Mineto Ota, Yasuo Nagafuchi, Shuji Sumitomo, Tomohisa Okamura, Keith B Elkon, Kazuyoshi Ishigaki, Akari Suzuki, Yuta Kochi, Kazuhiko Yamamoto, Keishi Fujio
bioRxiv 2021.10.08.463629; doi: https://doi.org/10.1101/2021.10.08.463629
Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus
Yusuke Takeshima, Yukiko Iwasaki, Masahiro Nakano, Yuta Narushima, Mineto Ota, Yasuo Nagafuchi, Shuji Sumitomo, Tomohisa Okamura, Keith B Elkon, Kazuyoshi Ishigaki, Akari Suzuki, Yuta Kochi, Kazuhiko Yamamoto, Keishi Fujio
bioRxiv 2021.10.08.463629; doi: https://doi.org/10.1101/2021.10.08.463629
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