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Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development
Vivian S. Park, Meijuan J.S. Sun, Wesley D. Frey, Leonard G. Williams, Karl P. Hodel, Juliet D. Strauss, Sydney J. Wellens, James G. Jackson, View ORCID ProfileZachary F. Pursell
doi: https://doi.org/10.1101/2021.10.10.463847
Vivian S. Park
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
Meijuan J.S. Sun
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
Wesley D. Frey
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
Leonard G. Williams
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
2BioInnovation Program, Tulane University, New Orleans, LA, USA
Karl P. Hodel
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
Juliet D. Strauss
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
Sydney J. Wellens
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
James G. Jackson
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
3Tulane Cancer Center, Tulane University School of Medicine, 1430 Tulane Ave., New Orleans, LA
Zachary F. Pursell
1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, New Orleans, LA, USA
3Tulane Cancer Center, Tulane University School of Medicine, 1430 Tulane Ave., New Orleans, LA
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Posted October 12, 2021.
Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development
Vivian S. Park, Meijuan J.S. Sun, Wesley D. Frey, Leonard G. Williams, Karl P. Hodel, Juliet D. Strauss, Sydney J. Wellens, James G. Jackson, Zachary F. Pursell
bioRxiv 2021.10.10.463847; doi: https://doi.org/10.1101/2021.10.10.463847
Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development
Vivian S. Park, Meijuan J.S. Sun, Wesley D. Frey, Leonard G. Williams, Karl P. Hodel, Juliet D. Strauss, Sydney J. Wellens, James G. Jackson, Zachary F. Pursell
bioRxiv 2021.10.10.463847; doi: https://doi.org/10.1101/2021.10.10.463847
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