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Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
Maria Georgiou, Chunbo Yang, Robert Atkinson, Kuan-Ting Pan, Adriana Buskin, Marina Moya Molina, Joseph Collin, Jumana Al-Aama, Franziska Goertler, Sebastian E. J. Ludwig, Tracey Davey, Reinhard Lührmann, Sushma Nagaraja-Grellscheid, Colin Johnson, Robin Ali, Lyle Armstrong, Viktor Korolchuk, Henning Urlaub, Sina Mozaffari-Jovin, Majlinda Lako
doi: https://doi.org/10.1101/2021.10.11.463925
Maria Georgiou
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Chunbo Yang
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Robert Atkinson
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Kuan-Ting Pan
2Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany
Adriana Buskin
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Marina Moya Molina
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Joseph Collin
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Jumana Al-Aama
3Faculty of Medicine, King Abdulaziz University, Saudi Arabia
Franziska Goertler
4Department of Biological Sciences, University of Bergen, Norway
Sebastian E. J. Ludwig
2Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany
Tracey Davey
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Reinhard Lührmann
2Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany
Sushma Nagaraja-Grellscheid
4Department of Biological Sciences, University of Bergen, Norway
5Department of Biosciences, Durham, UK
Colin Johnson
6Leeds Institute of Molecular Medicine, University of Leeds, UK
Robin Ali
7King’s College, London, UK
Lyle Armstrong
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Viktor Korolchuk
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
Henning Urlaub
2Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany
8Bioanalytics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany
Sina Mozaffari-Jovin
2Max-Planck Institute of Biophysical Chemistry, Göttingen, Germany
Majlinda Lako
1Newcastle University Biosciences Institute, Newcastle upon Tyne, UK
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Posted October 11, 2021.
Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
Maria Georgiou, Chunbo Yang, Robert Atkinson, Kuan-Ting Pan, Adriana Buskin, Marina Moya Molina, Joseph Collin, Jumana Al-Aama, Franziska Goertler, Sebastian E. J. Ludwig, Tracey Davey, Reinhard Lührmann, Sushma Nagaraja-Grellscheid, Colin Johnson, Robin Ali, Lyle Armstrong, Viktor Korolchuk, Henning Urlaub, Sina Mozaffari-Jovin, Majlinda Lako
bioRxiv 2021.10.11.463925; doi: https://doi.org/10.1101/2021.10.11.463925
Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
Maria Georgiou, Chunbo Yang, Robert Atkinson, Kuan-Ting Pan, Adriana Buskin, Marina Moya Molina, Joseph Collin, Jumana Al-Aama, Franziska Goertler, Sebastian E. J. Ludwig, Tracey Davey, Reinhard Lührmann, Sushma Nagaraja-Grellscheid, Colin Johnson, Robin Ali, Lyle Armstrong, Viktor Korolchuk, Henning Urlaub, Sina Mozaffari-Jovin, Majlinda Lako
bioRxiv 2021.10.11.463925; doi: https://doi.org/10.1101/2021.10.11.463925
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