Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons

Santulli Chiara; Bon Carlotta; De Cecco Elena; Codrich Marta; Narkiewicz Joanna; Parisse Pietro; Perissinotto Fabio; Claudio Santoro; Francesca Persichetti; Legname Giuseppe; Stefano Espinoza; Gustincich Stefano

doi:10.1101/2021.10.13.464204

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Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons

Santulli Chiara, Bon Carlotta, De Cecco Elena, Codrich Marta, Narkiewicz Joanna, Parisse Pietro, Perissinotto Fabio, Claudio Santoro, Francesca Persichetti, Legname Giuseppe, Stefano Espinoza, Gustincich Stefano

doi: https://doi.org/10.1101/2021.10.13.464204

Santulli Chiara

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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Bon Carlotta

2Central RNA Laboratory, Istituto Italiano di Tecnologia (IIT), Genova, Italy

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De Cecco Elena

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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Codrich Marta

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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Narkiewicz Joanna

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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Parisse Pietro

3ELETTRA Synchrotron Light Source, Trieste, Italy

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Perissinotto Fabio

3ELETTRA Synchrotron Light Source, Trieste, Italy

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Claudio Santoro

4Department of Health Sciences and Research Center on Autoimmune and Allergic Diseases (CAAD), University of Piemonte Orientale (UPO), Novara, Italy

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Francesca Persichetti

4Department of Health Sciences and Research Center on Autoimmune and Allergic Diseases (CAAD), University of Piemonte Orientale (UPO), Novara, Italy

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Legname Giuseppe

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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Stefano Espinoza

2Central RNA Laboratory, Istituto Italiano di Tecnologia (IIT), Genova, Italy

4Department of Health Sciences and Research Center on Autoimmune and Allergic Diseases (CAAD), University of Piemonte Orientale (UPO), Novara, Italy

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For correspondence: stefano.gustincich@iit.it stefano.espinoza@iit.it

Gustincich Stefano

1Area of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

2Central RNA Laboratory, Istituto Italiano di Tecnologia (IIT), Genova, Italy

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For correspondence: stefano.gustincich@iit.it stefano.espinoza@iit.it

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Posted October 14, 2021.

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Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons

bioRxiv 2021.10.13.464204; doi: https://doi.org/10.1101/2021.10.13.464204

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Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons

bioRxiv 2021.10.13.464204; doi: https://doi.org/10.1101/2021.10.13.464204

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