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Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer
Sohail Jahid, Jose A. Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppina La Sala, Jacopo Manigrasso, Jose M. Arencibia, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Andrea Armirotti, Rongsheng Jin, Zheng Liu, Chi-Fen Chen, Robert Edwards, Christopher C.W. Hughes, Marco De Vivo, Anand K. Ganesan
doi: https://doi.org/10.1101/2021.10.14.464305
Sohail Jahid
1Department of Dermatology, University of California, Irvine, Irvine, CA
Jose A. Ortega
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Linh M. Vuong
1Department of Dermatology, University of California, Irvine, Irvine, CA
Isabella Maria Acquistapace
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Stephanie J. Hachey
5Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA
Jessica L. Flesher
4Department of Biological Chemistry, University of California, Irvine, Irvine, CA
Maria Antonietta La Serra
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Nicoletta Brindani
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Giuseppina La Sala
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Jacopo Manigrasso
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Jose M. Arencibia
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Sine Mandrup Bertozzi
3Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Maria Summa
3Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Rosalia Bertorelli
3Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Andrea Armirotti
3Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Rongsheng Jin
5Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA
Zheng Liu
5Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA
Chi-Fen Chen
1Department of Dermatology, University of California, Irvine, Irvine, CA
Robert Edwards
6Department of Pathology and Lab Medicine, University of California, Irvine, Irvine, CA
Christopher C.W. Hughes
7Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA
Marco De Vivo
2Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy
Anand K. Ganesan
1Department of Dermatology, University of California, Irvine, Irvine, CA
4Department of Biological Chemistry, University of California, Irvine, Irvine, CA
Article usage
Posted October 14, 2021.
Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer
Sohail Jahid, Jose A. Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppina La Sala, Jacopo Manigrasso, Jose M. Arencibia, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Andrea Armirotti, Rongsheng Jin, Zheng Liu, Chi-Fen Chen, Robert Edwards, Christopher C.W. Hughes, Marco De Vivo, Anand K. Ganesan
bioRxiv 2021.10.14.464305; doi: https://doi.org/10.1101/2021.10.14.464305
Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer
Sohail Jahid, Jose A. Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher, Maria Antonietta La Serra, Nicoletta Brindani, Giuseppina La Sala, Jacopo Manigrasso, Jose M. Arencibia, Sine Mandrup Bertozzi, Maria Summa, Rosalia Bertorelli, Andrea Armirotti, Rongsheng Jin, Zheng Liu, Chi-Fen Chen, Robert Edwards, Christopher C.W. Hughes, Marco De Vivo, Anand K. Ganesan
bioRxiv 2021.10.14.464305; doi: https://doi.org/10.1101/2021.10.14.464305
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