New Results
Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
View ORCID ProfileShan Lu, Jiaojiao Hu, Bankhole Aladesuyi, View ORCID ProfileAlexander Goginashvili, View ORCID ProfileSonia Vazquez-Sanchez, Jolene Diedrich, View ORCID ProfileJinge Gu, Jacob Blum, Spencer Oung, View ORCID ProfileHaiyang Yu, View ORCID ProfileJohn Ravits, Cong Liu, View ORCID ProfileJohn Yates, View ORCID ProfileDon W. Cleveland
doi: https://doi.org/10.1101/2021.10.14.464447
Shan Lu
1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
Jiaojiao Hu
3Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
4University of Chinese Academy of Sciences, Beijing 100049, China
Bankhole Aladesuyi
5Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093
Alexander Goginashvili
1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
Sonia Vazquez-Sanchez
1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
Jolene Diedrich
6The Scripps Research Institute, La Jolla, CA 92037, USA
Jinge Gu
3Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
4University of Chinese Academy of Sciences, Beijing 100049, China
Jacob Blum
7Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
Spencer Oung
1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
Haiyang Yu
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
John Ravits
5Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093
Cong Liu
3Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
4University of Chinese Academy of Sciences, Beijing 100049, China
John Yates
6The Scripps Research Institute, La Jolla, CA 92037, USA
Don W. Cleveland
1Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA
2Ludwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA
5Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093
Article usage
Posted October 15, 2021.
Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
Shan Lu, Jiaojiao Hu, Bankhole Aladesuyi, Alexander Goginashvili, Sonia Vazquez-Sanchez, Jolene Diedrich, Jinge Gu, Jacob Blum, Spencer Oung, Haiyang Yu, John Ravits, Cong Liu, John Yates, Don W. Cleveland
bioRxiv 2021.10.14.464447; doi: https://doi.org/10.1101/2021.10.14.464447
Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
Shan Lu, Jiaojiao Hu, Bankhole Aladesuyi, Alexander Goginashvili, Sonia Vazquez-Sanchez, Jolene Diedrich, Jinge Gu, Jacob Blum, Spencer Oung, Haiyang Yu, John Ravits, Cong Liu, John Yates, Don W. Cleveland
bioRxiv 2021.10.14.464447; doi: https://doi.org/10.1101/2021.10.14.464447
Subject Area
Subject Areas
- Biochemistry (11715)
- Bioengineering (8723)
- Bioinformatics (29129)
- Biophysics (14936)
- Cancer Biology (12049)
- Cell Biology (17359)
- Clinical Trials (138)
- Developmental Biology (9406)
- Ecology (14144)
- Epidemiology (2067)
- Evolutionary Biology (18268)
- Genetics (12221)
- Genomics (16767)
- Immunology (11843)
- Microbiology (28014)
- Molecular Biology (11560)
- Neuroscience (60814)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3231)
- Physiology (4940)
- Plant Biology (10384)
- Synthetic Biology (2878)
- Systems Biology (7333)
- Zoology (1642)