Abstract
Haplotype-based scans to identify recent and ongoing positive selection have become commonplace in evolutionary genomics studies of numerous species across the tree of life. However, the most widely adopted approaches require phased haplotypes to compute the key statistics. Here we release a major update to the selscan software that re-defines popular haplotype-based statistics for use with unphased “multi-locus genotype” data. We provide unphased implementations of iHS, nSL, XP-EHH, and XP-nSL and evaluate their performance across a range of important parameters in a generic demographic history. Source code and executables are available at https://www.github.com/szpiech/selscan.
Competing Interest Statement
The authors have declared no competing interest.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Posted October 24, 2021.
