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The structure of a native orthobunyavirus ribonucleoprotein reveals a key role for viral RNA in maintaining its helical architecture
View ORCID ProfileFrancis R. Hopkins, Beatriz Álvarez-Rodríguez, View ORCID ProfileGeorge R. Heath, Kyriakoulla Panayi, View ORCID ProfileSamantha Hover, View ORCID ProfileThomas A. Edwards, View ORCID ProfileJohn N. Barr, View ORCID ProfileJuan Fontana
doi: https://doi.org/10.1101/2021.10.27.466080
Francis R. Hopkins
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
4Division of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden
Beatriz Álvarez-Rodríguez
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
5Institute for Integrative Systems Biology, I2SysBio (Universitat de València-CSIC), Paterna, Spain
George R. Heath
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
3School of Physics & Astronomy, Faculty of Engineering and Physical Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
Kyriakoulla Panayi
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
Samantha Hover
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
Thomas A. Edwards
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
John N. Barr
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
Juan Fontana
1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom
2Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
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Posted October 27, 2021.
The structure of a native orthobunyavirus ribonucleoprotein reveals a key role for viral RNA in maintaining its helical architecture
Francis R. Hopkins, Beatriz Álvarez-Rodríguez, George R. Heath, Kyriakoulla Panayi, Samantha Hover, Thomas A. Edwards, John N. Barr, Juan Fontana
bioRxiv 2021.10.27.466080; doi: https://doi.org/10.1101/2021.10.27.466080
The structure of a native orthobunyavirus ribonucleoprotein reveals a key role for viral RNA in maintaining its helical architecture
Francis R. Hopkins, Beatriz Álvarez-Rodríguez, George R. Heath, Kyriakoulla Panayi, Samantha Hover, Thomas A. Edwards, John N. Barr, Juan Fontana
bioRxiv 2021.10.27.466080; doi: https://doi.org/10.1101/2021.10.27.466080
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