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Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
View ORCID ProfileLivnat Jerby-Arnon, Katherine Tooley, Giulia Escobar, Gitanjali Dandekar, Asaf Madi, Ella Goldschmidt, Conner Lambden, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev
doi: https://doi.org/10.1101/2021.10.31.466532
Livnat Jerby-Arnon
1Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
2Chan Zuckerberg Biohub, San Francisco, CA 94158
3Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Katherine Tooley
4Evergrande Center for Immunologic Diseases, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA
5Division of Medical Sciences, Harvard Medical School, Boston, MA
Giulia Escobar
4Evergrande Center for Immunologic Diseases, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA
Gitanjali Dandekar
4Evergrande Center for Immunologic Diseases, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA
Asaf Madi
6Department of Pathology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Ella Goldschmidt
6Department of Pathology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Conner Lambden
4Evergrande Center for Immunologic Diseases, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA
Orit Rozenblatt-Rosen
3Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Ana C. Anderson
4Evergrande Center for Immunologic Diseases, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA
Aviv Regev
3Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
7Howard Hughes Medical Institute and Koch Institute of Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA
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Posted October 31, 2021.
Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
Livnat Jerby-Arnon, Katherine Tooley, Giulia Escobar, Gitanjali Dandekar, Asaf Madi, Ella Goldschmidt, Conner Lambden, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev
bioRxiv 2021.10.31.466532; doi: https://doi.org/10.1101/2021.10.31.466532
Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
Livnat Jerby-Arnon, Katherine Tooley, Giulia Escobar, Gitanjali Dandekar, Asaf Madi, Ella Goldschmidt, Conner Lambden, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev
bioRxiv 2021.10.31.466532; doi: https://doi.org/10.1101/2021.10.31.466532
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