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An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas
View ORCID ProfileDavid J. Falvo, Adrien Grimont, Paul Zumbo, View ORCID ProfileJulie L. Yang, Alexa Osterhoudt, Grace Pan, View ORCID ProfileAndre F. Rendeiro, John E. Wilkinson, Friederike Dündar, Olivier Elemento, Rhonda K. Yantiss, Doron Betel, Richard Koche, View ORCID ProfileRohit Chandwani
doi: https://doi.org/10.1101/2021.11.01.466807
David J. Falvo
1Department of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA
2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA
Adrien Grimont
1Department of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA
2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA
Paul Zumbo
3Institute for Computational Biomedicine, Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, 10065, USA
4Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, 10065, USA
Julie L. Yang
5Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
Alexa Osterhoudt
1Department of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA
2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA
Grace Pan
1Department of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA
2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA
Andre F. Rendeiro
3Institute for Computational Biomedicine, Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, 10065, USA
6Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10065, USA
John E. Wilkinson
7Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA
Friederike Dündar
3Institute for Computational Biomedicine, Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, 10065, USA
4Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, 10065, USA
Olivier Elemento
3Institute for Computational Biomedicine, Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, 10065, USA
6Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10065, USA
Rhonda K. Yantiss
8Department of Pathology, Weill Cornell Medicine, New York, NY, 10065, USA
Doron Betel
3Institute for Computational Biomedicine, Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, 10065, USA
4Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, 10065, USA
9Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, 10065, USA
Richard Koche
5Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
Rohit Chandwani
1Department of Surgery, Weill Cornell Medicine, New York, NY, 10065, USA
2Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, 10065, USA
10Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY, 10065, USA
Posted April 06, 2022.
An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas
David J. Falvo, Adrien Grimont, Paul Zumbo, Julie L. Yang, Alexa Osterhoudt, Grace Pan, Andre F. Rendeiro, John E. Wilkinson, Friederike Dündar, Olivier Elemento, Rhonda K. Yantiss, Doron Betel, Richard Koche, Rohit Chandwani
bioRxiv 2021.11.01.466807; doi: https://doi.org/10.1101/2021.11.01.466807
An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas
David J. Falvo, Adrien Grimont, Paul Zumbo, Julie L. Yang, Alexa Osterhoudt, Grace Pan, Andre F. Rendeiro, John E. Wilkinson, Friederike Dündar, Olivier Elemento, Rhonda K. Yantiss, Doron Betel, Richard Koche, Rohit Chandwani
bioRxiv 2021.11.01.466807; doi: https://doi.org/10.1101/2021.11.01.466807
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